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Efficacy of Light Therapy in Temporomandibular Dysfunction in people with different skin tones: a clinical study

Effectiveness of Photobiomodulation Therapy on Temporomandibular Dysfunction in patients with different skin phototypes: a double-blind randomized controlled trial

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
REBEC
Registry ID
RBR-73dm94r
Enrollment
Unknown
Registered
2025-04-29
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular dysfunction

Interventions

This is a four-arm, double-blind, randomized controlled clinical trial. The experimental groups (124 women) are as follows: Fitzpatrick I and II + Photobiomodulation Therapy (31 women), Fitzpatrick II
E02.594.540

Sponsors

Universidade de São Paulo
Lead Sponsor
Universidade de São Paulo
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 55 years; female gender; presence of reported pain in the facial region lasting at least three months; and presence of a diagnosis of myofascial pain according to the evaluation criteria of the revised version of the Diagnostic Criteria for Temporomandibular Disorders - DC/TMD (Axis I, categories Ia and Ib)

Exclusion criteria

Exclusion criteria: Women who are receiving any treatment for Temporomandibular Disorders or accumulate simultaneous interventions outside of this protocol; have a history of tumor, trauma or head and neck surgery; a previous diagnosis of fibromyalgia or other painful musculoskeletal syndromes; neurological and psychiatric disorders; use of anxiolytics, antidepressants and anticonvulsants; or who are pregnant

Design outcomes

Primary

MeasureTime frame
Pain reduction by Numerical Rating Pain Scale

Secondary

MeasureTime frame
Verification of Glutamate, Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), and Cortisol Levels.

Countries

Brazil

Contacts

Public ContactCarlos Girasol

Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto da Universidade de São Paulo

carlos.egirasol@gmail.com+55-016-33153670

Outcome results

None listed

Source: REBEC (via WHO ICTRP)