Left ventricular dysfunction, heart failure, Myocardial Ischemia
Conditions
Interventions
Patients with heart failure of ischemic etiology will be divided into two groups: supplemented and placebo group. The Group supplemented receive aqueous oral L-carnitine, providing 50mg/kg daily for 6
Dietary supplement
Sponsors
Universidade Federal Fluminense
Universidade Federal Fluminense
Eligibility
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Adults; lucid, oriented, both genders; greater than or equal to 18 years, less than or equal to 80 years, diagnosed with heart failure of ischemic etiology, NYHA functional class II and III; require coronary artery bypass grafting.
Exclusion criteria
Exclusion criteria: Renal dysfunction, hepatic dysfunction; disabsortive Syndromes; tumors, use of intra-aortic balloon; stroke, dysphagia, dialysis, sepsis, hemodynamic shock.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increasing the ejection fraction of the left ventricle determined by echocardiography at the end of the study compared to the beginning. | — |
Secondary
| Measure | Time frame |
|---|---|
| Supplementation with L-carnitine in patients who present Ejection Fraction Left Ventricular lower than 50%, established by echocardiography. | — |
Countries
Brazil
Contacts
Public ContactSheila Guimarães
Universidade Federal Fluminense
Outcome results
None listed