Renal Insufficiency Chronic, Muscle Weakness Sarcopenia
Conditions
Interventions
This randomized clinical trial will comprise four intervention groups, with a total sample of 56 participants equally distributed among four groups of 14 participants each: the Inspiratory Muscle Trai
Sponsors
Universidade Federal de Pernambuco
Lilian Maria Melo da Silva
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients diagnosed with chronic kidney disease stages 3 and 4; aged between 18 and 65 years; both sexes; patients under outpatient nephrology follow-up for at least 3 months
Exclusion criteria
Exclusion criteria: Patients with cognitive impairment; presence of acute respiratory infection; chronic obstructive pulmonary disease; decompensated heart failure; unstable angina; recent acute myocardial infarction; bedridden or wheelchair-bound patients with mobility limitations; patients with chronic kidney disease undergoing dialysis treatment; patients with grade II and III obesity; patients who regularly practice any type of physical activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that a difference will be found in respiratory muscle strength, maximum inspiratory pressure, and maximum expiratory pressure, both measured in centimeters of water; an increase in peripheral muscle strength of the lower limb will be found through the 30-second sit-to-stand test, and of the upper limb through dynamometry measured by a kilogram-force dynamometer | — |
Secondary
| Measure | Time frame |
|---|---|
| An increase in the forced expiratory volume in the first second is expected when using spirometry before and after training;An increase in forced vital capacity, expressed as a percentage using spirometry, is expected before and after training;It is expected to find an improvement in quality of life, assessed by the validated SF-36 questionnaire, measured on a scale of 0 to 100, which will be administered before and after training;An improvement in the Global Perception of Change, using a score of 0 to 7, is expected at the end of the training;Expect to see an increase in calf circumference thickness measured in centimeters at the end of the training;Expect to see an increase in gait speed test scores measured in seconds at the end of training;Expect to see an increase in Timed Up and Go measured in seconds at the end of the training;Changes and increases are expected in Body Mass Index measured in kilograms per square meter; weight, muscle mass, and fat mass, both measured in kilograms using a bioimpedance scale, at the end of the training;An improvement in lung tidal volume (VCctp), measured in liters (l), is expected to be observed using optoelectronic plethysmography in the pre- and post-intervention weeks;An improvement in the tidal volume of the thoracic and abdominal cavity (VCcta), measured in liters (l), is expected to be observed using optoelectronic plethysmography in the pre- and post-intervention weeks;An improvement in abdominal tidal volume (ACv), measured in liters (l), is expected to be observed using optoelectronic plethysmography in the pre- and post-intervention weeks;An improvement in inspiratory time (Ti), measured in seconds (s) using optoelectronic plethysmography, is expected to be observed in the pre- and post-intervention weeks;An improvement in expiratory time (Te), measured in seconds (s) using optoelectronic plethysmography, is expected in the pre- and post-intervention weeks;An improvement in total respiratory cycle time (Ttot), measur | — |
Countries
BR
Contacts
Public ContactLilian Melo da Silva
Universidade Federal de Pernambuco
Outcome results
None listed