Hemodilution
Conditions
Interventions
15 patients will be evaluated in a single arm, without masking or randomization. Cerebral oximetry will be recorded during acute normovolemic hemodilution, in a descriptive manner only.
Sponsors
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: The target population was patients undergoing general anesthesia for major non-cardiac surgeries; age were between 18 and 65 years old; classified as class I or II by the American Society of Anesthesiology; both male and female
Exclusion criteria
Exclusion criteria: Patients who refused or withdrew from participation were excluded. Patients with arrhythmias; heart failure; previous heart attacks; restrictive or obstructive lung diseases; significant renal dysfunction (creatinine clearance < 60 mg/L/min) or who had an oliguric or anuric presentation were also excluded; Patients with a preoperative hematocrit lower than 30% were also excluded, except in contexts in which the patient refused to receive blood transfusions, making this limitation less restrictive given the benefit in these cases; Patients undergoing laparoscopic surgeries; neurosurgeries; Surgeries in which neuraxial anesthesia was associated intraoperatively were also excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: description of linear regression between hematocrit drop during acute normovolemic hemodilution and cerebral oximetry during acute normovolemic hemodilution ;Observed outcome 1: A statistically significant linear regression was observed between hematocrit levels and cerebral oximetry during acute normovolemic hemodilution | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes were expected | — |
Countries
Brazil
Contacts
Public ContactSérgio Zuazo
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto
Outcome results
None listed