Pericoronitis
Conditions
Interventions
Patients included in the research will undergo extraction of two third molars. The extractions of the same patient will be performed with an interval of 3 weeks between them. One side that underwent e
MOMENI et al., 2021). Acetaminophen will be prescribed orally at a concentration of 500 mg, with ingestion every 8 hours (WEIL et al., 2007
KOPARAL et al., 2018
SAMPAIO-FILHO et al., 2018) during 3 postoperative days (FABRE et al., 2015). After extraction, the treatment for pain control will be chosen at random: Sham (S) or Photobiomodulation (PBM-T). Sham Gr
MOMENI et al., 2021), immediately after the suture, 24 hours and 48 hours after the surgical intervention (SAMPAIO-FILHO et al., 2018). Systemic PBM-T without light activation will be performed with t
PACHECO
BEZINELLI, 2018
PACHECO et al., 2018
ISABELLA et al., 2019
PACHECO et al., 2019). Acetaminophen will be prescribed by orally at a concentration of 500 mg, with ingestion every 8 hours (WEIL et al., 2007
SAMPAIO-FILHO et al., 2018) during 3 days postoperatively (FABRE et al., 2015).
Treatment Group (PBM-T) (n=45): Local and systemic PBM-T therapy. In patients in the PBM-T group, the local and systemic
E02.594
Sponsors
Pontifícia Universidade Católica de Campinas
Pontifícia Universidade Católica de Campinas
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients older than 18 years with an indication for third molar extraction; patients with indication for extraction of two erupted upper and/or lower third molars; patients or guardians who agree to participate in the research by signing the Informed Consent Form.
Exclusion criteria
Exclusion criteria: Patients with diabetes mellitus, cardiovascular disease, coagulation disorders, osteoporosis and/or hypertension; patients with psychological and/or neurological pathologies; patients with cysts, tumors and/or infection at the extraction site; pregnant or nursing women; immunosuppressed patients; drug-dependent patients; patients allergic to acetaminophen; patients using anticoagulants, antidepressants, benzodiazepines and/or bisphosphonates; patients who used analgesics, anti-inflammatory and/or antimicrobials two weeks before the study; patients who need other systemic medication in addition to paracetamol postoperatively.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of the study will be the assessment of pain before and after third molar extractions using the visual analogue scale (VAS) composed of a score from 0 to 10, where 0 indicates no pain, 1 to 3 mild pain, 4 to 6 moderate pain and 7 to 10 the worst possible pain. O The patient will report the intensity of pain he is feeling at the time of assessment using the VAS scale (HAMID, 2017; SAMPAIOFILHO et al., 2018; HOSSEINPOUR; TUNER; FEKRAZAD, 2019; KEYHAN et al., 2019; SINGH et al., 2019; ISOLAN et al., 2020; DOMAH et al., 2021; LODI et al., 2021; MOMENI et al., 2021). The application of the VAS scale will be before the surgical intervention, right after the suture, 24 hours, 48 ??hours and on the seventh postoperative day by an external examiner. | — |
Secondary
| Measure | Time frame |
|---|---|
| As a secondary outcome, the evaluation of edema will be carried out by the method of edema coefficients at different points (measured distance from the outer corner of the eye to the gonium and from the ear tragus to the labial commissure, using a measuring tape) (SINGH et al., 2019; DOMAH et al., 2021). O edema will be measured prior to the surgical intervention and also verified soon after the suture, 24 hours, 48 ??hours and on the seventh day after surgery by an external examiner. The formula for the coefficient of edema is the subtraction between the distance after and before surgery. The result is divided by the distance before surgery and the acquired number is multiplied by one hundred (SINGH et al., 2019). Another secondary outcome will be the application of the quality of life questionnaire using the 14-item Impact Profile on Oral Health (OHIP- 14), which is composed of questions related to personal well-being factors, such as functional, psychological, social and health experience factors. pain and discomfort. The OHIP-14 response format is: Always = 4; Often = 3; Almost always = 2; Sometimes = 1; Never = 0 (DUARTERODRIGUES et al., 2018; ABRAMOVITZ et al., 2021; LARSEN et al., 2021). The OHIP-14 score will be calculated as the sum of all 14 questions, ranging from 0 to 56 points, in the scoring system, the higher the OHIP-14 score, the greater the impact on the quality of life of the the lower the OHIP-14 score, the lower the impact on quality of life (DUARTE-RODRIGUES et al., 2018; ABRAMOVITZ et al., 2021; LARSEN et al., 2021). This assessment will be applied before the surgical intervention, right after the suture, 24 hours, 48 ??hours and in the seventh postoperative day by an external examiner. | — |
Countries
Brazil
Contacts
Public ContactCentro Vida
Outcome results
None listed