Muscle loss and atrophy, not elsewhere classified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 24 hours of invasive mechanical ventilation; being over 18 years old; present stable clinical conditions
Exclusion criteria
Exclusion criteria: pneumothorax, deep venous thrombosis and pulmonary thromboembolism, noradrenaline prescription, oxygenation index less than 150, recent history of deep venous thrombosis without use of anticoagulants, thrombocytopenia, hemodialysis patients, anasarca, prolonged weaning with failure in at least 3 tests spontaneous ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Muscle morphology, assessed by ultrasound through analysis of thickness, echo intensity, cross-sectional area, angle and length of the fascicle, up to 24h after admission to the ICU and every 3 days;Expected outcome 2: Muscle strength, assessed by the peak torque evoked up to 24h after admission to the ICU and every 3 days, and the MRC after awakening and every 3 days;Expected outcome 3: Functionality, assessed by the Barthel index on the day of discharge from the ICU and in the ward, and IMS - ICU mobility scale every 3 days in the ICU | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Time of mechanical ventilation, the duration of the use of invasive mechanical ventilation will be recorded using a form | — |
Countries
Brazil
Contacts
Universidade Federal do Vale do São Francisco