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Comparitive study between Carnoy and GEWF solutions for identifying lymph nodes in patients with cancer of the large bowel

Randomized clinical trial comparing Carnoy's and GEWF solutions for Lymph Node Clearing Technique in Colorectal Cancer

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6zc4cb
Enrollment
Unknown
Registered
2016-04-25
Start date
2015-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Colorectal adenocarcinoma patients, consecutively submitted to surgical treatment performed by colorectal surgeons with more than 10 years of professional experience at Hospital Moinhos de Vento (Por
Other

Sponsors

Hospital Moinhos de Vento
Lead Sponsor
Universidade Federal de Ciências da Saúde de Porto Alegre
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with histologically proven adenocarcinoma of the colon or rectum; both sexes; over 18 years of age; underwent surgical treatment performed by colorectal surgeons; agreement of the attending physician and the patient to participate in the study ;

Exclusion criteria

Exclusion criteria: Inaccuracy or unavailability of patient´s data.

Design outcomes

Primary

MeasureTime frame
Increased lymph node sample: additional number (unit measure) of lymph nodes identified by the lymph node clearing technique (visual and manual examination with Carnoy's or GEWF solutions) compared to the initial number (unit measure) of lymph nodes identified by the conventional technique (visual and manual examination with formaldehyde).

Secondary

MeasureTime frame
Change of lymph node staging: increase of lymph node staging status (migration from N classification to higher staging), according to the 7th edition of the American Joint Committee on Cancer, with the lymph node clearing technique (visual and manual examination with Carnoy's or GEWF solutions) compared to the initial lymph node staging by the conventional technique (visual and manual examination with formaldehyde).;Indication for adjuvant treatment: patient (unit measure) who had indication for adjuvant treatment (chemotherapy, radiotherapy or combined chemoradiotharepy) to treat colorectal cancer due to the outcome changes of the lymph node staging after using the lymph node clearing technique (visual and manual examination with Carnoy's or GEWF solutions).

Countries

Brazil

Contacts

Public ContactTiago Ghezzi

Hospital Moinhos de Vento

tlghezzi@terra.com.br+55(51)97256265

Outcome results

None listed

Source: REBEC (via WHO ICTRP)