Lower limb ulcer, not elsewhere classified
Conditions
Interventions
Experimental group: 25 patients with diabetes mellitus with wounds in the lower extremities will receive the application directly from the platelet-rich plasma wound once a week for 12 weeks or until
Other
Sponsors
Universidade Brasil
Universidade Brasil
Eligibility
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: Type I Diabetes Mellitus Type II; Chronic wound carrier (over 12 weeks) Both sexes; Age between 30 to 70 years; Controlled blood glucose; Normal peripheral platelet count.
Exclusion criteria
Exclusion criteria: Use of oral anticoagulants, Wound with osteomyelitis and / or with exposure of tendons or bones; Wound with local gangrene or close to the anatomical site. Patients with bleeding tendencies; Uncontrolled DM (HBA1C greater than 7.5); Serum albumin less than 2.5 g / dL; Hemoglobin less than 10.5 mg / dL; Malignant neoplasms; Lupus erythematosus; Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time, in weeks, for the treatment to promote the reepithelization and healing of chronic wounds of diabetic patients. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary 1: monitor, evaluate and analyze the use of the autologous PRP gel with optional therapy for the care of granulation and healing of chronic wounds in diabetic patients. ;Secondary 2: Evaluation of the quality of life of the patients being followed up in the study on the measurement of the type of pain at the beginning and at the end of the study using the validated Scale Verbal Numerica and LANSS, respectively. | — |
Countries
Brazil
Contacts
Public ContactCarla Tim
Universidade Brasil
Outcome results
None listed