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Evaluation of the effect of vitamin E supplementation on vitamin A values of mother and child

Evaluation of maternal vitamin E supplementation on retinol levels in serum and breast milk

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6ys9yp
Enrollment
Unknown
Registered
2017-08-24
Start date
2016-12-12
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin A deficiency

Interventions

The aim of this study was to evaluate the dose of maternal alpha-tocopherol supplementation in the increase and maintenance of retinol concentrations in blood and breast milk, as well as in the improv
Dietary supplement
SP6.051.227

Sponsors

Universidade Federal do Rio Grande do Norte - UFRN
Lead Sponsor
Universidade Federal do Rio Grande do Norte - UFRN
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Lactating women; normal birth; term delivery; age between 18 and 40 years.

Exclusion criteria

Exclusion criteria: Women with signs of clinical pathology; Infections; syphilis; HIV; Diseases of the gastrointestinal tract; Liver diseases; heart diseases; diabetes; hypertension; cancer; Mental disorder; Twin childbirth; Newborn with fetal malformations; Abortion history; Use of antithrombotics; Use of supplements containing vitamin E and / or A during pregnancy

Design outcomes

Secondary

MeasureTime frame
Expected outcome: The most significant increase and maintenance of the vitamin A level in breast milk of infants in the supplemented group 2 and 3. To confirm the expected outcome, statistical tools will be used to compare the efficiency of supplementation regimen 3 (administration of 2 capsules of 400 IU every 1 day postpartum) with supplementation regimen 2 (administration of 1 capsule of 400 IU on the 1st and 20th postoperative days) with supplementation regimen 1 (administration of 1 capsule of 400 IU in the 1 day postpartum).—

Primary

MeasureTime frame
Expected outcome: Increased retinol levels in maternal blood and milk following administration of vitamin E supplementation within 60 days postpartum. To verify the expected outcome, the efficiency of the three supplementation regimens adopted for the increase and maintenance of retinol levels in blood and breast milk in the determined period of time will be evaluated. Statistical tools will be used to verify variation in the retinol levels of the control, supplemented 1, supplemented 2 and supplemented groups 3.—

Countries

Brazil

Contacts

Public ContactJuliana Dametto

Universidade Federal do Rio Grande do Norte - UFRN

judamettonut@gmail.com+55(84)99914-3973

Outcome results

None listed

Source: REBEC (via WHO ICTRP)