Skip to content

Effect of a potassium nitrate dentifrice on tooth sensitivity caused by in-office dental bleaching.

Comparative study on the use of toothpaste with 5% potasium nitrate before the whitening process

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6ynq8f
Enrollment
Unknown
Registered
2020-05-14
Start date
2020-07-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth sensitivity

Interventions

Thirty eight volunteer participants will be included in this study, who will be divided in two groups (n = 19): the experimental and control group. The experimental group will receive a dentifrice con
Other

Sponsors

San Francisco of Quito University
Lead Sponsor
San Francisco of Quito University
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: This trial will include adults between 18 and 30 years old, regardless of gender, with good dental and periodontal health. Specifically attention will be given to six maxillary anterior teeth, which will be required to be caries-free and without buccal restorations. Shade of central incisors will be required to be A2 or darker in a value-oriented shade guide (VITA EasyShade Advance, Vita Zanhnfabrik).

Exclusion criteria

Exclusion criteria: This trial will exclude participants who have previously undergone tooth-bleaching procedures, dental sensitivity, pregnancy or lactation, and severe tooth pigmentation caused by drugs, fluorosis, or pulpal pathology. Participants will also be excluded if they are taking any form of medication (especially anti-inflammatory drugs), bruxism, enamel cracks, gingival recession, class V cavities, dentin exposure, or any other clinical condition that could cause dental sensitivity.

Design outcomes

Primary

MeasureTime frame
To assess the absolute risk of tooth sensitivity when using a dentifrice containing 5% potassium nitrate compared to a dentifrice without this active ingredient, related to an in-office tooth bleaching with 35% hydrogen peroxide.

Secondary

MeasureTime frame
Evaluate the effect of using a 5% potassium nitrate dentifrice in the whitening efficiency of 35% hydrogen peroxide by using a subjective method, such as the Vita Classical shade guide (Vita Lumin, Vita Zahnfabrik, Bad Säckingen, Germany), and an objective method, such as the spectrophotometer Vita Easy Shade (Vita Zahnfabrik, Bad Säckingen, Germany).

Countries

Ecuador

Contacts

Public ContactCarlos Dávila

San Francisco of Quito University

cadavilas@usfq.edu.ec+593 9 62794879

Outcome results

None listed

Source: REBEC (via WHO ICTRP)