Evaluation of the effectiveness of Propolis associated with Pomegranate in Treatment of the Buccal Inflammation due denture use in elderly

Evaluation of the effectiveness of Propolis associated with Pomegranate in the Denture Stomatitis Treatment in elderly

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

REBEC

Registry ID

RBR-6yf4cv

Enrollment

Unknown

Registered

2018-09-26

Start date

2018-07-11

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stomatitis, denture

Interventions

40 participants will be recruited, which will be distributed in 2 groups randomly

20 participants will be allocated to the propolis group (intervention) and 20 participantes will be allocated to the miconazole group (control). Participants will be instructed to apply thin layer of

Drug

D05.750.078.840.762

D03.383.129.308.550

E02.319

Eligibility

Age

60 Years to 99 Years

Inclusion criteria

Inclusion criteria: 60 years or older Use of partial or total dental prosthesis with palatal coverage Present denture stomatitis

Exclusion criteria

Exclusion criteria: Recent use of antibiotic or antifungal (2 months at least before the recruitment) Cognitive decline or dementia

Design outcomes

Primary

Measure	Time frame
Clinical cure rate of denture stomatitis lesions over than 70% verified by comparing Newton's classification in the 1st. and 14th. treatment days.	—

Secondary

Measure	Time frame
Decrease in the fungal load, assessed by number count of Colony Forming Units(CFU) of Candida sp at 14th day of treatment;Acceptance evaluation of the product through the application of the hedonic sensory scale, with a score above 6 points, evaluated in the 14th day of treatment	—

Countries

Brazil

Contacts

Public ContactYeda Parro

Universidade de Brasília

yedaparro@gmail.com+556131071802

Outcome results

None listed

Source: REBEC (via WHO ICTRP)