Prostatic Neoplasms
Conditions
Interventions
A randomized, controlled, non-blinded clinical trial will be carried out, where patients undergoing videolaparoscopic prostatectomy will be evaluated in a Brazilian tertiary university hospital, from
T2 (when the patient is placed in the Trendelemburg position with
D02.033.800.609
Sponsors
Hospital Universitário Onofre Lopes
Hospital Universitário Onofre Lopes
Eligibility
Sex/Gender
Male
Age
20 Years to 79 Years
Inclusion criteria
Inclusion criteria: Male gender; diagnosis of prostate cancer; age between 20 and 79 years
Exclusion criteria
Exclusion criteria: Patients with pathologies that increase intracranial pressure; previous neurosurgery; glaucoma; ophthalmological surgery; heart, liver or kidney failure; American Society of Anesthesiology classification more than III; patients who have surgery converted to open modality or who present hemodynamic instability during the transoperative period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluate the impact of Mannitol on intracranial pressure using the measurement of the optic nerve sheath diameter obtained through ultrasound using a 7.5MHz high frequency linear probe | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the difference in extubation time, awakening between cases and controls;Analyze the influence of other variables (mean arterial pressure, peak inspiratory pressure, ETCO2 and infused crystalloid volume) on measurements of the optic nerve sheath | — |
Countries
Brazil
Contacts
Public ContactWallace Da Silva
Hospital Universitário Onofre Lopes
Outcome results
None listed