Effects of Trunk-Specific Exercise on Pain, Inflammation, and Hormonal Release in Women with Back Pain

Acute neuroimunoendocrin effects of high and low volume core training in women with unspecific chronic low back pain: a crossover study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

REBEC

Registry ID

RBR-6wy5y4t

Enrollment

Unknown

Registered

2021-12-13

Start date

2019-10-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain

Interventions

26 volunteers will be selected to participate in the study. These volunteers will carry out two types of training. High volume core stability training (TAV) will consist of activating the deep trunk m

E02.760.169.063.500.387

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Women will be included in the research with a clinical diagnosis of nonspecific chronic low back pain, between 18 and 40 years old, who have complained of low back pain for more than 3 months, with a pain level between 3 and 6 on the Numeric Pain Rating Scale (NRS) (COSTA, et al. 2008). The volunteers will need to present a body mass index (BMI <30 kg/cm2); not being pregnant; not having given birth for less than three months; not having undergone any surgery on the spine; not having performed any type of exercise in the last three months; not being undergoing any type of pain treatment; and without the use of analgesic, anti-inflammatory, opioid or immunosuppressive medication.

Exclusion criteria

Exclusion criteria: Participants who miss one of the days of the tests or who have any psychiatric or cognitive impairment, hearing, visual or communication disorders that make it impossible to carry out the protocol will be excluded.

Design outcomes

Primary

Measure	Time frame
Evaluate the levels of Beta-endorphin, IL-6 and IL-10 verified through blood collection and analyzed by the ELISA method (enzyme-linked immunosorbent assay).	—

Secondary

Measure	Time frame
Assess the Pressure Pain Threshold (PPT) using the digital pressure algometer.;Assess conditioned pain modulation (CPM) with a digital pressure algometer and using ischemic compression as a conditioned stimulus.;Evaluate the central sensitization through the temporal summation test, evaluated with the digital pressure algometer.	—

Countries

Brazil

Contacts

Public ContactPoliana Santos

polianasantos.28@hotmail.com+55 (79) 99878-9989

Outcome results

None listed

Source: REBEC (via WHO ICTRP)