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Influence of smoking and its degree of dependence on quality of life and oral health

Influence of smoking on oral health related to quality of life, associated with the degree of dependence

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-6wy32ts
Enrollment
Unknown
Registered
2022-04-14
Start date
2019-04-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smokers

Interventions

12 smokers and 12 non-smokers with teeth diagnosed with Chronic Apical Periodontitis and indicated for extraction were selected. The lesions were collected, included in silanized slides and later stai
E06.645.700

Sponsors

Universidade Federal Fluminense
Lead Sponsor
Universidade Federal Fluminense
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Smoking and non smoking volunteers; both genders; 18 years of age or older; dental elements with clinical and radiographic diagnosis of Chronic Apical Periodontitis with indication for extraction

Exclusion criteria

Exclusion criteria: Teeth diagnosed with root fracture; previous endodontic treatment; and endo periodontal injury; individuals with systemic diseases; under the age of 18; users of anti-inflammatory and/or antibiotics in the last 3 months; drug users

Design outcomes

Primary

MeasureTime frame
It is expected to find higher expression of the RANKL protein and lower expression of the immunological biomarkers osteoprotegerin, osteopontin, tumor necrosis factor alpha, in smokers compared to non smokers—

Secondary

MeasureTime frame
Secondary outcomes are not expected—

Countries

Brazil

Contacts

Public ContactComitê de Ética e Pesquisa

Universidade Federal Fluminense

ceppunf@gmail.com+55 (22)2528-7168

Outcome results

None listed

Source: REBEC (via WHO ICTRP)