Hypertension
Conditions
Interventions
Experimental group: 30 hypertensive patients, both men and women, will receive beet juice (500ml), a drink rich in inorganic nitrate. Control group: 30 hypertensive patients, both men and women, will
Dietary supplement
SP6.051.227
Sponsors
Hospital Universitário Pedro Ernesto - HUPE
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro - FAPERJ
Eligibility
Age
45 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients of both sexes; age between 45 and 70 years; previous diagnosis of primary systemic arterial hypertension, signed the Informed Consent Term.
Exclusion criteria
Exclusion criteria: Secondary hypertension; systolic blood pressure greater than or equal to 180 mmHg or diastolic BP greater than or equal to 110 mmHg; in use of beta-blockers; with diabetes mellitus; history of cancer; in use of any dietary supplement; any serious life-threatening illness; cardiovascular diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the endothelial function of hypertensive patients after acute ingestion of beet juice. | — |
Secondary
| Measure | Time frame |
|---|---|
| Increased dilatation of the brachial artery, verified by means of the microvascular reactivity method, from the ingestion of beet juice, an inorganic nitrate rich drink, based on the variation of the percentage of increase of perfusion and percentage of increase of the area on the curve. | — |
Countries
Brazil
Contacts
Public ContactSamanta de Mattos
Hospital Universitário Pedro Ernesto - HUPE
Outcome results
None listed