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Use of Cashew Bark Extract in the treatment of Oral Lichen Planus

Use of curcumin and Cashew Bark Extract in the treatment of Oral Lichen Planus: randomized controlled clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
REBEC
Registry ID
RBR-6vmypw4
Enrollment
Unknown
Registered
2024-10-07
Start date
2023-07-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Therapeutics

Interventions

The present research consists of a controlled, randomized, single-blind and cross-sectional clinical trial study in patients diagnosed with oral lichen planus, who are divided into two groups, consist
D04.210.500.908.093.250

Sponsors

Programa de Pós-Graduação em Ciências Odontológicas - Universidade Federal do Rio Grande do Norte
Lead Sponsor
Programa de Pós-Graduação em Ciências Odontológicas - Universidade Federal do Rio Grande do Norte
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Cases of patients with symptomatic lichen planus located on the oral mucosa; patients aged 18 or over; both genders; patients who are not treated for other diseases with systemic corticosteroids

Exclusion criteria

Exclusion criteria: Pregnant or lactating women; patients with asymptomatic Oral Lichen Planus OLP; patients with a medical history of allergy to corticosteroids or hypersensitive to components of A. occidentale, such as phenols, or other plants from the Anacardiaceae Family; patients who received topical treatment for Oral Lichen Planus OLP two weeks before the start of the study; patients who received systemic treatment for Oral Lichen Planus -OLP four weeks before the start of the study; patients who do not show up for follow up

Design outcomes

Primary

MeasureTime frame
The outcome of this study is that the herbal gel-based intervention group will be as efficient as conventional corticosteroid-based treatment in treating OLP, however, without the commonly associated adverse effects. It is expected that more than 60% of the population studying in the intervention group (cashew tree shell gel) will present satisfactory results

Secondary

MeasureTime frame
No secondary outcomes are expected

Countries

Brazil

Contacts

Public ContactAnna Clara de Araújo

Programa de Pós-Graduação em Ciências Odontológicas - Universidade Federal do Rio Grande do Norte

annacodonto@gmail.com+55(84)998085599

Outcome results

None listed

Source: REBEC (via WHO ICTRP)