Carbohydrate Metabolism
Conditions
Interventions
This is a randomized, double-blind, crossover study with a one-week washout period (i.e., two sessions) involving 19 volunteers: 10 from the eutrophic group and 9 from the obese group. The study was r
Sponsors
Universidade Federal do Espírito Santo
Universidade Federal do Espírito Santo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: To be eligible, you must: be a person with a normal weight (BMI) between 18.5 and 24.9 kg/m2 who considers themselves healthy; or be an obese person with a BMI greater than 30.0 kg/m2; be a coffee consumer; not experience any side effects from consuming the beverage; be 18 years of age or older; and be of either sex
Exclusion criteria
Exclusion criteria: People living with diabetes; smokers; pregnant or breastfeeding women; people with intestinal diseases; cardiovascular diseases; hypothyroidism; hyperthyroidism; a history of alcohol and/or drug abuse/dependence; people using weight-loss or hypoglycemic medications, exogenous insulin, anti-inflammatory drugs, or antibiotics; or those using supplements containing caffeine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected that a smaller area under the curve of the analyzed incretins (GIP and GLP-1) will be found after ingestion of the glucose solution containing green coffee extract, using the Enzyme-Linked Immunosorbent Assay (ELISA) method and adopting a 5% probability. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that a smaller area under the glycemic curve will be found after ingestion of the glucose solution containing green coffee extract, using the colorimetric method for determination and adopting a 5% probability. | — |
Countries
Brazil
Contacts
Public ContactAndré Costa
Universidade Federal do Espírito Santo
Outcome results
None listed