Posttraumatic stress disorder.
Conditions
Interventions
20 individuals with Posttraumatic Stress Disorder diagnoses will undergo 6 Electroconvulsive therapy. In the experimental group 10 individuals will each application after reading a neutral text (no em
Procedure/surgery
F04.570.200.583
Sponsors
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - HCFMUSP
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - HCFMUSP
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 18 to 65. Complete diagnostic criteria for posttraumatic stress disorder (PTSD) by the DSM-IV. Identified by applying the Structured Clinical Interview for DSM Axis I Disorders. Meets the criteria of gravity and refractory to traditional treatments for PTSD, formulated on the basis of two studies that have shown efficacy and safety of therapeutic modality for PTSD (Helsley et al., 1999;. Margoob et al, 2010) or present clinical indication for ECT because of comorbidities. Provide skin conductance response and. To be able to understand and nod with the free and informed consent.
Exclusion criteria
Exclusion criteria: Have made abusive or recreational use of substances (except nicotine) less than 72 hours in the experimental days. Present relative contraindications to the use of ECT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of electrodermal activity upon to traumatic recall, tested one week after the completion of electroconvulsive therapy applications. Responses will be measured in microsiemens and square root transformed to normalize data. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reduction in scales that measure subjective responses to traumatic recall, applied one week after the completion of electroconvulsive therapy applications. Visual Analogous Scale, HAM-D, IDATE, DTS, IES-R. As there are no works with the same methodology, it is not possible to predict a magnitude of the reduction. | — |
Countries
Brazil
Contacts
Public ContactAlvaro;Felipe Araujo;Corchs
Instituto de Psiquiatria do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - IPq HCFMUSP;Instituto de Psiquiatria do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo - IPq HCFMUSP
Outcome results
None listed