Hypertension
Conditions
Interventions
Control group, clonidine will be made 150 mcg, IV (intravenous), with 31 patients.
Intervention group will be made metoprolol 10 mg, IV, with 31 patients. In either group, either clonidine, or metopro
Drug
D02.033.100.624.698.573
Sponsors
Hospital das Clínicas
Hospital das Clínicas
Eligibility
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients older than 18 years and up to 65 years old, hypertensive, who arrive at the surgical center to perform otorhinolaryngological surgeries
Exclusion criteria
Exclusion criteria: Patients with a heart rate of less than 60 beats per minute, patients with contraindication or allergy to clonidine or metoprolol, patients weighing less than 50 kg or patients weighing more than 100 kg, patients using a pacemaker
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure lower than 140 mmHg and diastolic blood pressure lower than 90 mmHg after the end of anesthesia. We will determine the percentage of patients who reach hypertensive patients at the surgical center, and at the end of surgery, they have normal blood pressure values | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic and diastolic blood pressure and heart rate measured every 15 minutes intraoperatively; postoperative heart rate, total dose of vasopressors, bleeding of the surgical field and postoperative bleeding, need for surgical reintervention after surgery, blood pressure measurement and heart rate four hours after discharge from the post-anesthetic recovery room between patients receiving clonidine and Metoprolol | — |
Countries
Brazil
Contacts
Public ContactSérgio Menezes
Hospital das Clínicas
Outcome results
None listed