Muscular Diseases
Conditions
Interventions
This is a controlled, observational, cross-sectional study. A group of 10 recipient patients underwent total intravenous general anesthesia for kidney transplantation, whose respective 10 donor patien
V03.175.500
Sponsors
Escola Paulista de Medicina da Universidade Federal de São Paulo
Escola Paulista de Medicina da Universidade Federal de São Paulo
Eligibility
Inclusion criteria
Inclusion criteria: Patients scheduled for living donor kidney transplantation; living patients scheduled for total nephrectomy for donation; both sexes
Exclusion criteria
Exclusion criteria: Patients with a previous history of intraoperative awakening; family or personal history of susceptibility to malignant hyperthermia (MH); contraindications to the use of halogenated inhaled anesthetics
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: Detection of halogenated inhalational anesthetics in the expired gas of a kidney transplant recipient who underwent total intravenous anesthesia. An increase in halogenated inhalation anesthetics concentration is expected in the period immediately following reperfusion of the transplanted kidney, verified using the anesthetic gas meter based on the observation of a variation of at least 0.1% in pre- and post-reperfusion measurements ;Outcome found 1: An increase in halogenated inhalation anesthetics concentration of 0.1%was observed in the period immediately following reperfusion of the transplanted kidney, verified using the anesthetic gas meter, in two patients from sevoflurane group | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: Detection of halogenated inhalational anesthetics in the perfusion solution of the harvested kidney. But It was not possible to perform this measurement;Outcome found 2: It was not possible to perform this measurement of halogenated inhalational anesthetics in the perfusion solution of the harvested kidney | — |
Countries
Brazil
Contacts
Public ContactMarcia Santos
Escola Paulista de Medicina da Universidade Federal de São Paulo
Outcome results
None listed