Endodontics
Conditions
Interventions
It will include 84 volunteer patients requiring endodontic treatment (root canal therapy) will be divided into three groups who will receive the drugs prior to the initiation of the treatment in order
Group 2 (n=28) 8mg dexamethasone 1 hour prior the treatment
Group 3 (G3, 28), placebo control (flour capsule, 1 hour prior the treatment). All medicines will be administered in a single oral dose. Patients will be advised to use analgesic medication support (
Drug
Procedure/surgery
V03.175.250.500.500
D26.660
E06.397
Sponsors
Universidade Estadual de Ponta Grossa
Universidade Estadual de Ponta Grossa
Eligibility
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Healthy volunteers; both genders; age between 18 and 60 years; signed consent form; endodontic treatment needs; symptomatic; ability to understand the pain scales and questionnaires.
Exclusion criteria
Exclusion criteria: Use of analgesics or anti-inflammatories drugs within 12 hours before the endodontic procedure; acute dento-alveolar or periodontal abscess; needs of antibiotic prophylaxis; pregnant or lactating; mental disability; systemic alterations or allergies that contraindicate the use of the anti-inflammatories.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The patients after the use of the preoperative drugs and endodontic treatment the analysis of the intensity of the postoperative pain will be done with two scales: numerical rate scale - 101 points (NRS-101) and visual analog scale (VAS) after 4, 8, 12 , 24, 48 and 72 hours.Thus, it is expected to verify whether the use of anti-inflammatory drugs in the preoperative can contribute to pain control in the post root canal treatment.;The results showed that the placebo group members experienced more post-endodontic pain and discomfort since they had an increase of rescue medication consumption in comparison with the ibuprofen and dexamethasone groups. On the order hand, there was no statistical difference between the ibuprofen and dexamethasone groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary variables such as gender, age, anxiety, initial pain intensity, diagnosis of the dental element, duration of the surgical procedure, anesthetic technique used, number of anesthetic tubes, time of care and use of support medication will also be considered and the relationship with post-operative pain. The data will be based on parametric and non-parametric statistical models.;The secondary variables gender, age, anxiety, diagnosis, duration of the procedure, number of anesthetic cartidges had no significant relationship with pain and they had the same distribution between groups. | — |
Countries
Brazil
Contacts
Public ContactFábio dos Santos
Universidade Estadual de Ponta Grossa
Outcome results
None listed