tooth erosion, dental pellicle
Conditions
Interventions
This is an efficacy study. This is an in situ, crossover, blinded, experimental interventional study with 4 experimental phases of 9 days each. The sample size was calculated based on a study with a s
brushing with 1450 ppm sodium fluoride toothpaste + rinsing with 0.4% tin fluoride solution (phase 2)
brushing with 0.454% tin fluoride toothpaste (phase 3)
brushing with 0.454% tin fluoride toothpaste + rinsing with 0.4% tin fluoride solution (phase 4). Individuals will use a mandibular intraoral appliance containing 6 specimens of bovine enamel and dent
E06.761.726.794
Sponsors
Universidade Federal do Rio Grande do Sul
Universidade Federal do Rio Grande do Sul
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: individuals of both sexes; aged 18 years or older; good general health
Exclusion criteria
Exclusion criteria: individuals who have self-reported gastroesophageal reflux; pregnant women; individuals using orthodontic appliance; individuals with special needs; individuals with difficulties in understanding the protocol and its guidelines
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a lower average surface loss (µm) in enamel and dentin blocks after exposure to the combined use of stannous fluoride dentifrice and stannous fluoride mouthwash. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find a protein profile more associated with proteins resistant to acidification after exposure to the combined use of toothpaste with stannous fluoride and mouthwash containing stannous fluoride. | — |
Countries
Brazil
Contacts
Public ContactRodrigo Arthur
Universidade Federal do Rio Grande do Sul
Outcome results
None listed