Communicable Diseases Infections
Conditions
Interventions
This is an observational, cross-sectional, and descriptive study conducted between September 2023 and August 2025, using a convenience sample of hospitalized patients at INI–Fiocruz who were assessed
the SARC-F questionnaire
the Timed Up and Go test
the sit-to-stand test
the 4-meter gait speed test
the Chair Stand Test
the 2-minute stationary march test
the Romberg test
measurement of maximal static respiratory pressures
and functional assessment using the mobility scale.
Sponsors
Instituto Nacional de Infectologia Evandro Chagas - INI/Fiocruz
Instituto Nacional de Infectologia Evandro Chagas - INI/Fiocruz
Eligibility
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: Participants of both sexes; aged between 18 and 79 years, who met hospital discharge criteria were included in the study and were subsequently divided into two groups.The first group (G1) consisted of patients considered fit to perform physical tests for functional assessment and who did not present the following conditions: (1) abdominal aortic aneurysm; (2) functional class IV dyspnea according to the New York Heart Association classification; (3) presence of drains; (4) continuous intravenous infusion; (5) pain scored as 8 on the visual analog scale; (6) osteomuscular disease preventing assessment; (7) nothing by mouth (NPO) status; and (8) deep vein thrombosis.The second group (G2) consisted of patients not fit to perform physical tests for functional assessment due to presenting one or more of the conditions described above, and their functional status was evaluated only using the Barthel Index.
Exclusion criteria
Exclusion criteria: The following were considered exclusion criteria: hemodynamic instability; delirium; cognitive impairment preventing understanding of the tests; refusal to participate in the study; and inability to communicate verbally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A reduction in the functionality of patients hospitalized for infectious diseases at the time of hospital discharge is expected. This outcome will be verified using standardized functional assessment instruments, including the Barthel Index, mobility tests, physical performance assessment, and muscle strength measurements. The scores obtained from these instruments will be observed and compared to the predicted values for the reference population, considering cutoff points, means, and expected percentages for each age group, in order to determine whether the results found are below the established normative parameters. | — |
Secondary
| Measure | Time frame |
|---|---|
| A reduction in autonomy for performing activities of daily living at the time of hospital discharge is expected, as assessed by the Barthel Index. Functional decline will be considered present if the Barthel Index score is lower than 85 at discharge.;A reduction in muscle mass during hospitalization is expected. This outcome will be verified through the assessment of bioelectrical impedance analysis results. Differences between the values obtained from patients classified as having functional decline and those without functional decline—defined based on functional tests—will be analyzed, considering a statistically significant difference when p = 0.05 (5% significance level).;A reduction in peripheral muscle strength at the time of hospital discharge is expected. This outcome will be verified through the assessment of handgrip strength. The values obtained will be compared with the predicted values according to sex at birth, based on a specific reference equation, in order to identify reductions relative to the expected parameters.;A reduction in respiratory muscle strength is expected during hospitalization. This outcome will be assessed by measuring maximal Inspiratory pressure. The obtained values will be compared to predicted values according to sex and age, based on reference equations, in order to identify any reduction relative to the expected parameters.;An association between patient functionality and hospital length of stay is expected. This association will be assessed by evaluating patient functionality and recording the duration of hospital stay. Standardized functional indices (e.g., independence or functional capacity scales) and total length of stay in days will be used to identify correlations between lower functionality and longer hospitalization. | — |
Countries
BR
Contacts
Public ContactMônica da Cruz
Instituto Nacional de Infectologia Evandro Chagas - INI/Fiocruz
Outcome results
None listed