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Changes in heart rate and immediate blood pressure and after different protocols of breathing exercises in patients with Chagas' heart disease.

Acute and subacute hemodynamic changes in individuals with chronic chagasic cardiopathy submitted to different respiratory muscular training protocols - Clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6qw5sp
Enrollment
Unknown
Registered
2020-01-07
Start date
2019-04-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chagas' disease (chronic) with heart involvement

Interventions

A minimum of 20 participants will be required to perform the study, subjects will undergo two different inspiratory muscle training protocols (IMT), one aiming at endurance training and the other with
Other
E02.190.525.186

Sponsors

Instituto Nacional de Infectologia Evandro Chagas
Lead Sponsor
Instituto Nacional de Infectologia Evandro Chagas
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Male and female gender; be over 18 years old; having stage B2 and C chagasic heart disease; be in regular follow-up at the Chagas disease outpatient clinic of the Evandro Chagas National Institute of Infectious Diseases (INI).

Exclusion criteria

Exclusion criteria: Clinically decompensated individuals; who have chronic lung disease; who have atrial fibrillation; pacemaker carriers; who present some clinical limitation that contraindicates the performance of the proposed exercise protocol; pregnant women.

Design outcomes

Primary

MeasureTime frame
A greater reduction in systolic, diastolic and mean blood pressure, as measured by plethysmography, is expected immediately after and within 60 minutes after the respiratory muscle training maneuver comparing the difference between the strength protocol group to the the endurance protocol group.—

Secondary

MeasureTime frame
A greater increase in heart rate, as measured using a cardiofrequencimeter, is expected immediately after and within 60 minutes after the respiratory muscle training maneuver comparing the difference between the strength protocol group to the the endurance protocol group.;A greater increase in myocardial work, stimated by doble-product (measured by the multiplication of systolic blood pressure by heart rate), is expected immediately after and within 60 minutes after the respiratory muscle training maneuver comparing the difference between the strength protocol group to the the endurance protocol group.—

Countries

Brazil

Contacts

Public ContactAline Frota

Instituto Nacional de Infectologia Evandro Chagas

alineifrj@gmail.com+55 21 993634430

Outcome results

None listed

Source: REBEC (via WHO ICTRP)