Skip to content

Effect of exercise and muscle electrical contraction on the critical patient defense system

Effect of physical exercise and functional electrical stimulation on the immune system of critical patients

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
REBEC
Registry ID
RBR-6pxpx9
Enrollment
Unknown
Registered
2018-09-21
Start date
2013-11-05
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammatory polyneuropathy, unspecified

Interventions

This is a randomized controlled clinical trial of patients admitted to the ICU of the Agamenon Magalhães Hospital (AMH) in mechanical ventilation for less than 48 hours that meet the inclusion criteri
Group 2: Approximately 10 patients who will be submitted to passive physical exercise (physical exercise group - PEG)
Group 3: Approximately 10 patients who will undergo FES (functional electrical stimulation group - FESG) and Group 4: Approximately 10 patients who will be submitted to association of the passive phys
Other
E02.760.169.063.500.387
G61.9
E05.723.402

Sponsors

Hospital Agamenon Magalhães
Lead Sponsor
Hospital Agamenon Magalhães
Collaborator

Eligibility

Age
21 Years to 80 Years

Inclusion criteria

Inclusion criteria: Critical patients; submitted to mechanical ventilation; no signs of hypertension or hypotension; normal electrocardiogram; show no signs of respiratory distress; clinical-laboratory tests within normal values.

Exclusion criteria

Exclusion criteria: Patient with signs of intracranial hypertension; inability to walk without assistance before acute illness in the ICU; pregnant women; obese; use of cardiac pacemaker; diagnoses of neurological, vascular, orthopedic and oncological pathologies.

Design outcomes

Primary

MeasureTime frame
Reduction of inflammatory cytokine values by at least 5% of the baseline values, measured by laboratory tests before and one hour after the intervention;Reduction of monocyte-mediated cellular nitric oxide values by at least 10% of baseline values, measured by laboratory tests before and one hour after the intervention

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactEduardo França

Hospital Agamenon Magalhães

edueriko@hotmail.com55-081-988775859

Outcome results

None listed

Source: REBEC (via WHO ICTRP)