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Use of medications in preventing sensitivity arising from tooth bleaching.

Use of medications in preventing sensitivity arising from tooth bleaching. - : Dental Bleaching, Dentin Sensitivity, Dexamethasone

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-6pt2n3
Enrollment
Unknown
Registered
2015-04-29
Start date
2013-12-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Sensitivity, Dental Bleaching

Interventions

Experimental group: Thirty patients will take an anti-inflammatory drug (dexamethasone 8 mg) 1 hour before the bleaching protocol. Additional doses of dexamethasone (4 mg) will be administered every
Drug
Other
E06.420.750

Sponsors

Universidade Estadual de Ponta Grossa - UEPG
Lead Sponsor
Universidade Estadual de Ponta Grossa - UEPG
Collaborator

Eligibility

Age
18 Years to 34 Years

Inclusion criteria

Inclusion criteria: Patients older than 18 years are included, with good oral and general health, with free maxillary anterior teeth restorations and do not carious lesion present, that have the color of A1 or darker teeth according to the color scale Classical Vita (Vita Zahnfabrik, Bad Säckingen, Germany).

Exclusion criteria

Exclusion criteria: Patients who already underwent tooth whitening, pregnant or lactating patients, who report tooth sensitivity, severe browning (staining tetracycline, fluorosis or endodontics), with parafunctional habits, patients with dental prostheses and appliances Orthodontic and any other oral pathology will be deleted. Still be excluded patients who have systemic symptoms such as problems stomach, heart, kidney and liver, diabetes, hypertension or who are making continuous use of any medication with analgesic action and anti-inflammatory

Design outcomes

Primary

MeasureTime frame
Expected outcome: Number of patients that report spontaneous pain in any moment of the bleaching protocol and up to 48 h post-bleaching, through self-report. This number will be presented as percentage of patients with tooth sensitivity and will be named absolute risk of tooth sensitivity ;Observed outcome: The same expected outcome. No change in the outcome was done.

Secondary

MeasureTime frame
Expected outcome: The intensity of tooth sensitivity will be assessed using the numeric 5-point scale (NRS 0-4) and the visual analogue scale (VAS 0-10) and will be presented as means and standard deviations in different periods (during dental bleaching, up to 1 h, 1 h to 24 h and 24 h to 48 h post-bleaching).;Observed outcome: The same expected outcome. No change in the outcome was done.;Expected outcome: The difference in color between the baseline condition and 1 month post-bleaching will be assessed by Vita Classical and Bleachedguide Vita shade guide as well as with the Vita Easyshade spectrophotometer. The data will be presented as means and standard deviations;Observed outcome: The same expected outcome. No change in the outcome was done.

Countries

Brazil

Contacts

Public ContactStella Pereira

Universidade Estadual de Ponta Grossa - UEPG

stellakp@gmail.com+55 (42) 32203741

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 24, 2026