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Evaluation of tooth whitening performed with 16% carbamide peroxide with or without very small hydroxyapatite particles

Clinical evaluation of efficacy and sensitivity during home bleaching with 16% Carbamide Peroxide added with Hydroxyapatite nanoparticles

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6pmkr5w
Enrollment
Unknown
Registered
2025-06-02
Start date
2024-02-05
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth Discoloration

Interventions

The population of this randomized controlled, parallel, four-arm, triple-blind clinical trial will be composed by 48 men and women, from 18 to 50 years old, who are unpleased with the color of their t
D02.065.950.278

Sponsors

Faculdade de Odontologia da Universidade do Estado do Rio de Janeiro
Lead Sponsor
Hospital Universitário Pedro Ernesto da Universidade do Estado do Rio de Janeiro
Collaborator

Eligibility

Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Those individuals who have anterior teeth free of carious lesions and without restorations on the buccal and palatal surfaces will be included in the clinical trial; who do not present tooth sensitivity (sensitivity stimulated with an air syringe); patients from 18 to 50 years old; patients with any kind of color (VITA color guide); patients who were able to read and sign the consent form and are willing to attend follow-up visits

Exclusion criteria

Exclusion criteria: Patients with systemic diseases; whitening performed six months ago or less; patients who underwent scaling less than 6 months ago; those allergic to peroxide; those with neoplasia; patients with dentin sensitivity equal to or greater than mild; teeth with severe internal discoloration (tetracycline stains, fluorosis or teeth without pulp); patients with amelogenesis; patients with habits such as smoking, chewing toothpicks or with parafunctional habits; patients with periodontal disease or undergoing treatment for periodontal disease; patients who had non-carious cervical lesions or anterior teeth with exposed incisal dentin; pregnant and lactating women

Design outcomes

Primary

MeasureTime frame
A reduction of tooth sensitivity with the use of whitening gels with the addition of hydroxyapatite nanoparticles is expected.

Secondary

MeasureTime frame
It is expected that the hydroxyapatite nanoparticles will not compromise the whitening potential of carbamide peroxide.

Countries

Brazil

Contacts

Public ContactRudá Moreira

Faculdade de Odontologia da Universidade do Estado do Rio de Janeiro

ruda.moreira@uerj.br+55(21)993478525

Outcome results

None listed

Source: REBEC (via WHO ICTRP)