Osteoarthritis
Conditions
Interventions
This study will be a randomized, two-arm, prospectively and masked trial of patients and evaluators. In total, 40 patients with knee osteoarthritis will perform a standardized exercise protocol involv
Other
G11.427.410.698.277
Sponsors
Universidade Federal do Rio Grande do Norte
Universidade Federal do Rio Grande do Norte
Eligibility
Age
50 Years to 90 Years
Inclusion criteria
Inclusion criteria: Are 50 years of age or more; Have a body mass index (BMI) of up to 35 kgm-2; Have moderate to very severe knee osteoarthritis (score between 5 and 13 on the Lequesne Questionnaire); Have score of 24 or more on Mini-Mental State Examination; Do not have peripheral vascular disease, systolic blood pressure greater than 160 or smaller than 100mmHg, diastolic blood pressure greater than 100mmHg, deep vein thrombosis, history of myocardial infarction, stroke in the last year or history of cancer; Do not have other orthopedic problems that affect gait and do not present other inflammatory myoarticular or neurological diseases; Have not undergone surgery or any invasive procedure for the knees in the last 6 months; Not participating in physiotherapeutic treatment or lower limb strengthening programs in the past three months; Not practicing regular physical activity (two or more times per week) for lower limbs (except for those who only practice walking).
Exclusion criteria
Exclusion criteria: Experience pain that prevents completely the exercises proposed by two consecutive sessions or three non-consecutive or who refuse to remain in the study; Begin taking medications that interfere with study outcomes or begin to exercise or other treatment modalities for knee OA after the initiation of treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee pain at rest and during walking assessed by means of the mean difference in visual analog pain scale before, after 12 weeks of treatment and 3 months after the end of treatment (follow-up). | — |
Secondary
| Measure | Time frame |
|---|---|
| Functionality assessed by the mean difference in the physical function tests and the Lequesne's questionnaire before, after 12 weeks of treatment and 3 months after the end of treatment (follow-up).;Quality of life assessed by mean difference in the SF-36 questionnaire before, after 12 weeks of treatment and 3 months after the end of treatment (follow-up).;Muscle performance assessed by the mean difference in isokinetic, isometric and 7-10 maximal repetitions test before, after 12 weeks of treatment and 3 months after the end of treatment (follow-up).;Perceived knee pain and exertion perceived assessed during all exercise sessions by mean difference in the visual analog scale and the Borg scale in all treatment sessions.;Patient adherence and satisfaction with treatment assessed by means of the completed sessions and the mean difference in Feeling Scale and overall effect perception assessed during treatment sessions after 12 weeks of treatment and 3 months after the end of treatment (follow-up). | — |
Countries
Brazil
Contacts
Public ContactMikhail Santos Cerqueira
Universidade Federal do Rio Grande do Norte
Outcome results
None listed