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Physical exercise can reduce the accumulation of fat, improve the immunity and quality of blood in people living with HIV/aids.

Effects of a program of physical exercise in body composition, immune system and blood changes of people living with HIV/AIDS: a clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6p9ncq
Enrollment
Unknown
Registered
2018-07-04
Start date
2015-01-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human immunodeficiency virus - HIV

Interventions

The intervention was carried out in the gym of the Center of excellence in physical activity of the EMU. Concurrent training (CT) was performed 3 times a week (3 times a week) for 12 weeks. The aerobi
and 3) shoulder development (OD)
4) Earth squatting (AT)
7) Straight abdominal. Adaptation to training (AT) was performed two sets of ten to twelve repetitions (2 x 10-12 repetitions) with loads adjusted for free choice during the first two weeks of trainin
Other
G11.427.410.698.277
G11.427.410.698.277.311.250
E02.760.169.063.500.387.875

Sponsors

Universidade Estadual de Maringá
Lead Sponsor
Universidade Estadual de Maringá
Collaborator

Eligibility

Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; both genders; age between 18 and 50 years; carriers of the HIV virus; regular users of antiretroviral therapy; sedentary.

Exclusion criteria

Exclusion criteria: Volunteer smokers; alcohol abuse; physical limitation for exercise; chronic diseases; cardiorespiratory diseases; diagnoses of cardiac, renal, gastrointestinal, hepatic, pulmonary, neurological, psychiatric, hematological or metabolic disorders; disuse of therapy; incorrect training.

Design outcomes

Primary

MeasureTime frame
Outcome 1: Methods. Analysis of the adipocyte area: 30 images of each sample stained with hematoxylin and eosin (HE) were captured in a 20X objective. Of all the images captured by sampler, 10 were selected for the analysis of the area (m2) of adipocytes (Image Pro Plus®, Media Cybernetics, Silver Spring, Maryland, USA). In each image, from eight to twelve adipocytes were measured, totaling one hundred adipocytes, on average, per sample. Results: The control group (HIV-) presented before the training the mean values of the adipocyte area of 6917.2 m2 and after training this average reduced to 4653.5 ?m2. In the group living with HIV (HIV +) we found averages before training of 5477.3 m2 and after training this average reduced to 3775.9 m2, demonstrating the effect of training for both groups.;Outcome 2: Method. Histogram analysis: Categorization of the adipocyte size classes was performed to categorize the information collected in the adipocyte analysis data to verify the heterogeneity of the information contained in the data, using the STURGES formula; and the mixed effects model for analyzing categorical data, considering the statistical P less than 0.05. Results: When analyzing the number of adipocytes in different class intervals, it was observed that the HIV + group at the beginning of the training had a higher amount of adipocytes in a range of classes of smaller size than the HIV- (P <0, 05). However, after training, this difference was no longer significant, although both groups reduced the size of class intervals in the post-training period compared to the pre-period (P <0.05).

Secondary

MeasureTime frame
Secondary outcome: Performance analysis: for the measurement of aerobic capacities, the velocity test (Vpico) was used on a treadmill with an initial velocity of 7 km / h with increments of 1 km / ha every 3 minutes after a previous heating of 5 minutes at 5 km / h. Results: Peak velocity analyzed in the control group (HIV-) was initially from 9.09 km / h to 10.70 km / h after the intervention and the HIV + group left 8.91 km / h before training and went to 10.09 km / h after training.

Countries

Brazil

Contacts

Public ContactBruno Ferrari Silva

Universidade Estadual de Maringá

brunoferrarisilva@live.com+55-044-30111379

Outcome results

None listed

Source: REBEC (via WHO ICTRP)