Human immunodeficiency virus - HIV
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Healthy volunteers; both genders; age between 18 and 50 years; carriers of the HIV virus; regular users of antiretroviral therapy; sedentary.
Exclusion criteria
Exclusion criteria: Volunteer smokers; alcohol abuse; physical limitation for exercise; chronic diseases; cardiorespiratory diseases; diagnoses of cardiac, renal, gastrointestinal, hepatic, pulmonary, neurological, psychiatric, hematological or metabolic disorders; disuse of therapy; incorrect training.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Outcome 1: Methods. Analysis of the adipocyte area: 30 images of each sample stained with hematoxylin and eosin (HE) were captured in a 20X objective. Of all the images captured by sampler, 10 were selected for the analysis of the area (m2) of adipocytes (Image Pro Plus®, Media Cybernetics, Silver Spring, Maryland, USA). In each image, from eight to twelve adipocytes were measured, totaling one hundred adipocytes, on average, per sample. Results: The control group (HIV-) presented before the training the mean values of the adipocyte area of 6917.2 m2 and after training this average reduced to 4653.5 ?m2. In the group living with HIV (HIV +) we found averages before training of 5477.3 m2 and after training this average reduced to 3775.9 m2, demonstrating the effect of training for both groups.;Outcome 2: Method. Histogram analysis: Categorization of the adipocyte size classes was performed to categorize the information collected in the adipocyte analysis data to verify the heterogeneity of the information contained in the data, using the STURGES formula; and the mixed effects model for analyzing categorical data, considering the statistical P less than 0.05. Results: When analyzing the number of adipocytes in different class intervals, it was observed that the HIV + group at the beginning of the training had a higher amount of adipocytes in a range of classes of smaller size than the HIV- (P <0, 05). However, after training, this difference was no longer significant, although both groups reduced the size of class intervals in the post-training period compared to the pre-period (P <0.05). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome: Performance analysis: for the measurement of aerobic capacities, the velocity test (Vpico) was used on a treadmill with an initial velocity of 7 km / h with increments of 1 km / ha every 3 minutes after a previous heating of 5 minutes at 5 km / h. Results: Peak velocity analyzed in the control group (HIV-) was initially from 9.09 km / h to 10.70 km / h after the intervention and the HIV + group left 8.91 km / h before training and went to 10.09 km / h after training. | — |
Countries
Brazil
Contacts
Universidade Estadual de Maringá