Acute myocardial infarction, Oxidative stress
Conditions
Interventions
This is an observational cohort study with 84 patients who suffered acute myocardial infarction. No control group was used and the patients did not undergo a randomization process. At the end of the s
C14.907.585
Sponsors
Unidade de Emergência do Hospital das Clínicas de Ribeirão Preto
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP)
Eligibility
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients diagnosed with acute myocardial infarction with ST segment elevation; male and female; of different races; aged 18 years or older within 72 hours of hospital admission
Exclusion criteria
Exclusion criteria: Patients with diagnosis of renal or hepatic disease; cancer; age over 80 years; use of external orthopedic or cardiac devices; mechanical ventilation; pregnancy; cardiorespiratory arrest or cardiogenic shock at admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcomes were defined by the incidence of major cardiovascular events within 12 months of follow-up, including all-cause mortality, cardiovascular mortality, new acute coronary syndrome, new stroke, or hospitalization for heart failure. The incidence of new events was observed in approximately 13% of the study population, totaling 11 patients | — |
Secondary
| Measure | Time frame |
|---|---|
| Considering the inflammatory parameters, it was found that patients who developed new events within 12 months had higher interleukin 6 levels. Based on the assessment of oxidative stress, it was found that patients who developed new events had higher total antioxidant capacity. Regarding anthropometric data and body composition, it was found that patients who presented new events had a lower phase angle, lower fat-free mass index, lower arm circumference, calf circumference, adductor pollicis muscle and lower intracellular water levels | — |
Countries
Brazil
Contacts
Public ContactClara Passos
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP)
Outcome results
None listed