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Influence of bleaching agent application times on the effectiveness and safety of in-office tooth whitening

Influence of 37.5% hydrogen peroxide application times on the effectiveness and safety of in-office tooth bleaching: a double-blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-6nv76g
Enrollment
Unknown
Registered
2020-09-09
Start date
2017-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tooth whitening, tooth sensitivity.

Interventions

Objective to evaluate, through a randomized clinical trial, the influence of different application times of hydrogen peroxide at 37.5% on the efficaccy and safety of dental bleaching in the office. Th
Procedure/surgery
E06.420.750
V03.175.250.400

Sponsors

Universidade Federal da Paraíba
Lead Sponsor
Universidade Federal da Paraíba
Collaborator

Eligibility

Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: The six maxillary anterior teeth had to be present, with a shade mean C2 or darker; to be at least 18 years of age; the anterior maxillary and mandibular teeth should not have more than 1/6 of the buccal surface covered with a restorative material; to be with good dental and general health.

Exclusion criteria

Exclusion criteria: Individuals with or to be treated for active caries or periodontal diseases; with visible cracks in maxillary or mandibular anterior teeth; evident malocclusion or under orthodontic treatment; parafunctional habits; severe internal tooth discoloration (tetracycline, fluorosis or pulpless teeth); tooth sensitivity; previous bleaching treatment; smokers; pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: The primary outcome of the study was the tooth color improvement that was measured with a spectrophotometer. Data were collected at baseline, 1 month, six and twelve months after treatment.;Expected outcome 2: The second primary outcome was the reduction of risk and intensity of tooth sensitivity, which were measured daily (for 21 days), from the first day of treatment, using a numerical rating scale.

Secondary

MeasureTime frame
Improvement of self-perception regarding dental esthetics measured using a visual analog scale before and after treatment.

Countries

Brazil

Contacts

Public ContactSônia Meireles Monte Raso

Universidade Federal da Paraíba

soniasaeger@hotmail.com+55-083-999467971

Outcome results

None listed

Source: REBEC (via WHO ICTRP)