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Effect of the use of a cream with leucine and lactic acid associated with electrostimulation in contouring facial

Development of a cream containing leucine and lactic acid to increase facial muscle tone in adult women

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6nv3c5
Enrollment
Unknown
Registered
2019-12-11
Start date
2015-10-26
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Women

Interventions

Experimental Group (EG): 15 participants, use of the leucine-based cream and lactic acid + electrostimulation for facial toning (mean intensity 13 Hz and protocol in progression)
and Control group: 15 participants, use of the placebo cream (without addition of leucine and lactic acid) + stimulation with the same protocol of GEG. Each group used daily their cream and underwent
Other

Sponsors

Universidade Norte do Paraná
Lead Sponsor
Universidade Norte do Paraná
Collaborator

Eligibility

Sex/Gender
Female
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Female sex; be healthy; body mass within the range of 15% of the weight considered normal for men and women, taking into account height and physical structure; skin photo type 1 to 4 (color of skin)

Exclusion criteria

Exclusion criteria: Present any type of physical or mental diseases, which interfere with the use of cream in a continuous form and in the evaluation measures, have carried out some sort of facial surgery, deficiency or absence of cutaneous sensibility, presence of scars, allergies, hematoma and/or abrasions on the face, perform any type of treatment in aesthetic centers during the study period. Women were also excluded from the study with occurrence of tooth pain, pregnant or lactating diseases with infectious process and/or inflammatory process in facial region, acne grade 3, use of pacemakers and metal plates.

Design outcomes

Primary

MeasureTime frame
“Expected Outcome 1”. It was expected to find improvement in facial contour in the experimental group when compared to the control;Outcome 1: Significant improvement found in facial contour analyzed by photogrammetry (Experimental group = 19 degrees increase vs. control = 6 degrees)

Secondary

MeasureTime frame
outcome 2: improved muscle activation in the experimental group when compared to the control group;The muscular tonus improved in both groups, with an increase in the muscular activity of the masseter (average 28%) in the task smile

Countries

Brazil

Contacts

Public ContactRubens da Silva

Universidade Norte do Paraná

rubensalex@hotmail.com+55 43 33717700

Outcome results

None listed

Source: REBEC (via WHO ICTRP)