Pre-eclampsia
Conditions
Interventions
This is a randomized, placebo-controlled, double-blind clinical study. Experimental group: 60 women supplemented with capsules containing 600 mg of N-acetylcysteine ??(NAC), once a day, after a main m
Sponsors
Universidade Federal de Alagoas
Hospital Universitário Professor Alberto Antunes
Eligibility
Sex/Gender
Female
Age
11 Years to No maximum
Inclusion criteria
Inclusion criteria: Women; adolescents and adults; between 24 and 28 weeks of gestation; diagnosed with pre-eclampsia; attended prenatal care at the Professor Alberto Antunes University Hospital
Exclusion criteria
Exclusion criteria: Multiple pregnancies; women with neurological disorders and comorbidities that may influence the outcomes of pregnancy (diabetes mellitus, cardiovascular problems, urinary tract infection, kidney disease, autoimmune diseases, hepatitis, syphilis, human immunodeficiency virus, among others); as well as pregnant women who are alcoholics; smokers; those who use antioxidant and/or anti-inflammatory drugs; pregnant women whose newborns have serious malformations (cardiac, renal or hepatic) or genetic syndromes diagnosed during prenatal care
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find improvements in perinatal outcomes, such as birth weight and length | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess biomarkers of redox imbalance and inflammation | — |
Countries
Brazil
Contacts
Public ContactAlane Oliveira
Universidade Federal de Alagoas
Outcome results
None listed