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Is the esthetic effect of Botox influenced by physical exercise

Durability of the aesthetic applications of Botulinum Toxin type A in practitioners of high intensity physical exercise

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
REBEC
Registry ID
RBR-6ms6sns
Enrollment
Unknown
Registered
2023-01-05
Start date
2022-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Exercise

Interventions

This is a 3-arm, blinded, controlled clinical study. A total of 60 people who meet the eligibility criteria will be allocated using the classification of the International Physical Activity Questionna

Sponsors

Centro Universitário Ingá - UNINGÁ
Lead Sponsor
Centro Universitário Ingá - UNINGÁ
Collaborator

Eligibility

Sex/Gender
Female
Age
25 Years to 50 Years

Inclusion criteria

Inclusion criteria: Volunteers with complain of dynamic wrinkles; moderate or severe dynamic forehead and glabellar lines according to the Merz 5-point scale; never received botulinum toxin type A injections in any area of the face.

Exclusion criteria

Exclusion criteria: Volunteers that received Antitetanic vaccination and any chemical peel in the past 6 months; no esthetics procedures that could affect forehead and glabellar regions in the previous 12 months; with autoimmune disease; current use of drugs that act at neuromuscular junctions.

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: It is expected to find a reduction in muscle contraction in a period of three months, verified through the method of Electromyography (EMG);Outcome found 1: A significant decrease in muscle contraction was observed after 2 months, verified through the method of Electromyography (EMG)

Secondary

MeasureTime frame
Expected outcome 2:It is expected to find a reduction in the severity of dynamic wrinkles in a period of three months, verified using the Merz 5-point and Face-Q scale method.;Outcome found 2:A significant decrease in the amount of severe dynamic wrinkles was observed after 3 months, verified using the Merz 5-point and Face-Q scale method.

Countries

Brazil

Contacts

Public ContactGiancarlo De la Torre Canales

Centro Universitário Ingá - UNINGÁ

giank_28@hotmail.com+55 44 3033 5009

Outcome results

None listed

Source: REBEC (via WHO ICTRP)