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Impact of Rapid Maxillary Expansion with Orthodontic Appliance on Oral Microbiome and Inflammation

Effects of Rapid Maxillary Expansion with dental anchorage using orthodontic bands and gun bases and the impact on the oral microbiome and inflammatory intervals

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6mnr6jb
Enrollment
40
Registered
2026-03-13
Start date
2026-02-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Palatal Expansion Technique Inflammation

Interventions

This is a randomized, longitudinal, comparative clinical study with two parallel groups, which will include 40 children of both sexes, aged between 6 and 11 years, randomly distributed into two groups

Sponsors

Faculdade de Odontologia de Piracicaba da Universidade Estadual de Campinas
Lead Sponsor
Faculdade de Odontologia de Piracicaba da Universidade Estadual de Campinas
Collaborator

Eligibility

Age
6 Years to 11 Years

Inclusion criteria

Inclusion criteria: Volunteers aged 6 to 11 years with a clinical diagnosis of unilateral or bilateral posterior crossbite and/or maxillary atresia; Class I or Class II dental malocclusion; first or intertransitional period of mixed dentition; absence of extensive caries lesions and periodontal disease, good general and oral health; absence of previous orthodontic treatment

Exclusion criteria

Exclusion criteria: Volunteers with conditions that compromise oral health at the time of the initial evaluation; with systemic diseases or general health conditions that may interfere with treatment or clinical evaluations; with a history of previous orthodontic treatment; with craniofacial anomalies, genetic syndromes, or cleft lip and palate; continuous or recent use of medications

Design outcomes

Primary

MeasureTime frame
The aim is to determine whether the type of dental anchorage influences the results of Rapid Maxillary Expansion, considering orthodontic (evaluation of digital models) and periodontal (clinical, radiographic and microbiological) aspects.

Secondary

MeasureTime frame
An improvement in the oral microbiome is expected with anchorage using a bonding base

Countries

BR

Contacts

Public ContactSilvia Vedovello

Faculdade de Odontologia de Piracicaba da Universidade Estadual de Campinas

silviavedovello@gmail.com+55 (19) 98128-0787

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 4, 2026