Skip to content

Oral minoxidil 2.5 mg versus 5 mg for the treatment of male Pattern Hair Loss: a double-blind randomized clinical trial

Oral minoxidil 2.5 mg versus 5 mg for the treatment of male Androgenetic Alopecia: a double-blind randomized clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
REBEC
Registry ID
RBR-6mjd8bx
Enrollment
Unknown
Registered
2022-08-03
Start date
2022-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Androgenetic alopecia

Interventions

Group 1: 45 participants will use 1 pill of minoxidil 2.5mg per day for 24 weeks. Clinical and trichoscopic photos will be taken before the pill and at the end of 24 weeks. Group 2: 45 participants wi
51334
9103

Sponsors

Faculdade de Medicina de Botucatu
Lead Sponsor
Hospital das Clínicas de Botucatu
Collaborator

Eligibility

Sex/Gender
Male
Age
25 Years to 55 Years

Inclusion criteria

Inclusion criteria: male; aged between 25 and 55 years; diagnosis of androgenetic alopecia; classified on the Norwood Hamilton scale as 3V, 4V or 5V; agreeing to participate in the research

Exclusion criteria

Exclusion criteria: previous treatment for hair loss in the last 4 months; hypertensive patients; patients with heart disease; nephropathy; hepatopathy; patients with pheochromocytoma; patients with other causes of hair loss or scalp dermatoses

Design outcomes

Primary

MeasureTime frame
To evaluate the variation in the density of terminal hairs of the target area before the beginning of the treatment and after 24 weeks verified by the method of analysis of the trichoscopic photos. We will observe numbers of terminal wires, considering those with a thickness greater than 0.04 mm. The expectation is for an increase of 35 terminal hairs/cm2 in the group that will receive 5 mg/day against 12 terminal hairs/cm2 in the group that will receive 2.5 mg/day.

Secondary

MeasureTime frame
Evaluate density variation by counting total hairs in the target area and using a 7-point comparison scale, using the standardized clinical photography assessment method by 3 dermatologists blinded to the treatment and self-assessment of patients. Higher density is expected in the group receiving 5mg/day of oral minoxidil.

Countries

Brazil

Contacts

Public ContactLarissa Fonseca

Faculdade de Medicina de Botucatu

larissapcarvalho9@gmail.com+55 (14) 3880-1259

Outcome results

None listed

Source: REBEC (via WHO ICTRP)