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Clinical cohort of children with microcephaly associated with Congenital Zika Infection in Pernambuco

Clinical cohort of children with microcephaly and other abnormalities associated with congenital zika infection in Pernambuco

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-6m8zhy
Enrollment
Unknown
Registered
2017-12-14
Start date
2015-10-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Zika, Virus, Children, Microcephaly

Interventions

Cohort study about Zika virus in 1000 pregnants and children with clinical follow up of children during 3 years for clinical evaluation of neurodevelopment using Bayley Test 3rd edition.
Other

Sponsors

Fundação Oswaldo Cruz
Lead Sponsor
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Collaborator

Eligibility

Age
1 Days to 3 Years

Inclusion criteria

Inclusion criteria: Pregnant women with cutaneus rash and children with microcephaly and oothers children com microcefalia and others clinical conditions related to Zika Virus

Exclusion criteria

Exclusion criteria: Pregnant women with rash caused by others provd Arboviroses infection or infection by TORCHS group

Design outcomes

Primary

MeasureTime frame
Rates of Mycrocephaly and others neurological abnormalities: seizures and Developmental delay;Microcephaly is beeing defined by Head circunference less than -2 z-scores using as reference Intergrowth curve, seizures in EEG and Developmental delay proved by Bayley Test (Scales of Infant and Toddler Development- third edition)

Secondary

MeasureTime frame
rate of Dysphagia is defined by the rate of difficulty of swallowing and frequent choking

Countries

Brazil

Contacts

Public ContactRicardo Ximenes

Fundação Oswaldo Cruz

raaximenes@uol.com.br55 (81) 2101-2500/2600

Outcome results

None listed

Source: REBEC (via WHO ICTRP)