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Effect of drug therapy in the treatment of migraine

Additional effect of physical therapy to drug treatment in reducing the intensity and frequency of migraine - a randomized controlled trial - ADERE: ADditional Effect of physical therapy to drug treatment in REducing the intensity and frequency of migraine - a randomized controlled trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Observational
Source
REBEC
Registry ID
RBR-6kvx74
Enrollment
Unknown
Registered
2012-04-26
Start date
2011-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine without aura, myofascial pain syndromes, Limitations of the Cervical Range of Motion

Interventions

Group of drugs: 25 volunteers will be instructed to taken orally (25 mg) of amitriptyline at night for two months and will be allowed to use up to 600mg of Ibuprofen in cases of crisis stronger. Gr
other
E02.779.483.750
E02.190

Sponsors

Faculdade de Medicina de Ribeirão preto da Universidade de São Paulo
Lead Sponsor
Departamento de Biomecânica Medicina e Reabilitação do Aparelho Locomotor.
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Will be included 50 individuals with migraine, female, aged between 18 and 55. Will be considered only patients with at least two attacks and a maximum of 12 days of pain per month, with disease duration longer than one year, they are only in ambulatory treatment with amitriptyline up to 25 mg for at least 3 months.

Exclusion criteria

Exclusion criteria: Will be excluded women with diagnoses of other concurrent headache diagnosis of migraine, history of cervical trauma and face, with uncontrolled systemic diseases affecting the musculoskeletal system, peripheral nervous system diseases, which have physical therapy in the last one year specific to region or craniocervical posture and have some clinical contraindication to the use of amitriptyline as cardiac arrhythmias, glaucoma and epilepsy.

Design outcomes

Secondary

MeasureTime frame
Increased pressure pain threshold in kg in muscle in craniofacial demonstrated displey pressure algometer. ;Increase in neck range of motion in degrees using the Cervical Range of Motion (CROM).

Primary

MeasureTime frame
Reduced Frequency (in days) and intensity (in hours) of by Migraine headache diary.

Countries

Brazil

Contacts

Public ContactMaria Gonçalves

Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

mcgfisio@yahoo.com.br(16)xx36024413

Outcome results

None listed

Source: REBEC (via WHO ICTRP)