Diabetic foot
Conditions
Interventions
This is a randomized, clinically controlled longitudinal study conducted to evaluate the difference in wound size reduction in diabetic foot ulcers using an innovative protocol in combination with an
(ii) electrophysical protocol (high-frequency therapy + pulsed ultrasonic therapy + laser)
(iii) green synthetic gel (Aloe Vera) with silver nanoparticles
and (iv) electrophysical protocol + green synthetic gel (Aloe Vera) with silver nanoparticles. Patients in the 4 groups will undergo 2 treatment sessions per week for 3 months, for a total of 24 sessi
E02.565.280.945
E02.779.468
Sponsors
Claudio Teodoro de Souza
Universidade Federal de Juiz de Fora
Eligibility
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Agree to participate in the study (sign the informed consent form); diagnosis of type 1 or 2 diabetes; present chronic wounds (wounds that do not close after 6 weeks); grade 2 wound, according to Wagner's classification (DIABETIC FOOT ULCER CLASSIFICATION SYSTEMS, 2016), which is: neuropathic and deeper, often penetrating the subcutaneous tissue, has infection, but without bone involvement, purulent secretion, inflammation and cellulitis.
Exclusion criteria
Exclusion criteria: Ingesting any supplement that aids healing, in pre- and post-operative procedures (e.g. impact diet); infected ulcer accompanied by cellulitis; osteomyelitis; received or will receive radiation during the study; had constant alcohol abuse 3 months before the start of the research; diagnosed with cancer; presence of wounds containing necrotic tissue, slough or fibrin necrosis; and inability of the patient to continue attending the clinic during follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate whether the retraction (in percentage) of the diabetic foot wound area is improved after the combination of electrophysical devices and nanoparticle ointment when compared with conventional treatment (control) | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate whether better wound retraction is related to anti-inflammatory and antioxidant markers and growth factors after the combination of electrophysical devices and nanoparticle ointment when compared with conventional treatment (control) | — |
Countries
Brazil
Contacts
Public ContactClaudio de Souza
Universidade Federal de Juiz de Fora
Outcome results
None listed