Muscle Fatigue
Conditions
Interventions
This is a 12-week, unblinded, randomized clinical trial involving individuals with low to moderate levels of physical activity, who will be randomly assigned to three parallel experimental groups: the
which will follow a physical exercise protocol), the green tea kombucha group (n=30
which will follow a physical exercise protocol and consume 200 mL of green tea kombucha daily), and the grape kombucha group (n=30
which will follow a physical exercise protocol and consume 200 mL of green tea kombucha produced with phenolic extract from grape skin daily). The physical exercise protocol will consist of physical t
Sponsors
Departamento de Nutrição e Saúde da Universidade Federal de Viçosa
Departamento de Tecnologia de Alimentos da Universidade Federal de Viçosa
Departamento de Educação Física da Universidade Federal de Viçosa
Universidade Federal de Viçosa
Eligibility
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Men and women; aged between 18 and 45 years; body mass index between 18.5 and 24.9 kg/m²; with low to moderate levels of physical activity, assessed by the International Physical Activity Questionnaire – short version (IPAQ)
Exclusion criteria
Exclusion criteria: Individuals with chronic diseases or disorders affecting the digestive, oral, hepatic, renal, cardiovascular, or thyroid systems; individuals with cancer; inflammatory diseases or eating disorders; those who have used anti-inflammatory drugs, corticosteroids, or antibiotics in the past three months; pregnant, breastfeeding, or menopausal women; individuals who use tobacco and/or drugs; those with alcohol consumption exceeding 21 units per week for men and 14 units per week for women; individuals undergoing nutritional counseling for muscle mass gain; those who use antioxidant nutritional supplements; individuals with present or recurrent musculoskeletal injuries; those who frequently consume Kombucha, other fermented foods, or green tea; individuals with an aversion to Kombucha
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find an improvement in oxidative stress after 12 weeks of kombucha consumption, with a 10% increase in Total Plasma Antioxidant Capacity, assessed by the method of Benzie & Strain (1996) | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find modulation of the salivary and intestinal microbiota through the 16S sequencing method, based on the change in the composition of abundance and diversity of bacteria considering an alpha of 5% compared to the beginning of the study;It is expected to find a decrease in cardiometabolic, inflammatory, intestinal permeability, and DNA methylation parameters by laboratory analytical methods according to the protocol recommended by the manufacturer, of at least 5% compared to the value at the beginning of the study;It is expected to find a 5% improvement in physical performance compared to baseline, as assessed by specific physical tests | — |
Countries
Brazil
Contacts
Public ContactJosefina Bresssan
Departamento de Nutrição e Saúde da Universidade Federal de Viçosa
Outcome results
None listed