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Evaluation of the Use of Antiseptic Nose For Decolonization of Resistant Bacteria in Hospitals

Evaluation of the efficacy of nasal application of silver sulfadiazine for decolonization of patients with methicillin-resistant Staphylococcus aureus in hospitals

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6gs2jh
Enrollment
Unknown
Registered
2015-04-24
Start date
2014-02-25
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Human patients infected

Interventions

Will be included 50 patients in the treatment group and 50 in the placebo group with swab of the anterior nostrils positive for Methicillin-resistant Staphylococcus aureus. These patients suffer colle
Drug
D02.065.884.725.755.800

Sponsors

Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Lead Sponsor
Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to 120 Years

Inclusion criteria

Inclusion criteria: Patients admitted in the Hospital das Clinicas, Ribeirão Preto Medical School, University of Sao Paulo; age over 18 years; isolation of methicillin-resistant Staphylococcus aureus.

Exclusion criteria

Exclusion criteria: Volunteers carry cystic fibrosis; patients with chronic osteomyelitis; carry infection related to foreign body; topic pregnancy with a live fetus; negative nasal swab for methicillin-resistant Staphylococcus aureus.

Design outcomes

Primary

MeasureTime frame
Difference between the number of patients decolonized by Methicillin-resistant Staphylococcus aureus after decolonization therapy in the experimental group with silver sulfadiazine and placebo group. The evaluation of nasal decolonization be performed by culturing for MRSA nasal swabs.

Secondary

MeasureTime frame
Difference between the number of patients infected by Methicillin-resistant Staphylococcus aureus after decolonization therapy in the experimental group with silver sulfadiazine and placebo group. The evaluation of the incidence of infection will be performed by the Hospital Infection Control Committee.

Countries

Brazil

Contacts

Public ContactLécio Ferreira

Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo

leco.rfr@gmail.com+55 (16) 99305 8230

Outcome results

None listed

Source: REBEC (via WHO ICTRP)