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Phototherapy and blood flow restriction to protect against muscle damage

Photobiomodulation versus ischemia in protection against exercise-induced muscle damage: a clinical trial analyzing functional, perceptual and biochemical markers

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6gr5kf
Enrollment
Unknown
Registered
2020-02-19
Start date
2025-04-30
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Interventions

This is a randomized, placebo-controlled, double-blind clinical trial to be conducted with 45 young, healthy men with no recent experience in upper limb strength training, aged between 18 and 35 years

Sponsors

Universidade Estadual do Sudoeste da Bahia
Lead Sponsor
Universidade Estadual do Sudoeste da Bahia
Collaborator

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Be a healthy male, aged 18-35 years and classified as irregularly active or active in the International Physical Activity Questionaire (IPAQ); Not being involved in strength training programs for upper limbs; not with a body mass index (BMI) of less than 18.5 kg / m-2 and greater than 30 kg / m-2; not be smokers or who use vasoactive medications and nutritional supplements regularly. Do not report musculoskeletal injury to lower limbs within 3 months prior to testing; not having uncontrolled diabetes mellitus or blood pressure; have no inflammatory rheumatologic condition or severe cardiovascular and / or pulmonary disease that prevents them from performing the evaluation and the proposed exercise; not having psychiatric disease and malignant tumors; not have presented Zika or Chikungunya in the last year

Exclusion criteria

Exclusion criteria: Missing some day of collection; at any time and for any reason expressing an intention to leave the study; present a health problem that prevents them from continuing to participate in the research; use of medications, electrotherapeutic equipment or other therapeutic resources to improve pain and performance during the collection period; practicing unusual or strenuous physical activities during the days of collection; Volunteers who smoke; history of alcohol or drug abuse

Design outcomes

Primary

MeasureTime frame
Delayed-onset muscle soreness measured by the visual analogue pain scale (VAS) of 100 millimeters, where 0 is understood as no pain and 100 as the largest pain ever experienced by the volunteer. An average difference of at least 20 points in the EVA is expected

Secondary

MeasureTime frame
Isometric torque measured by isokinetic dynamometer;Knee range of motion measured by goniometry. A 5 to 50% change in range of motion is expected;Thigh circumference measured by perimetry. A change of 5 to 50% in circumference is expected;Serum creatine kinase levels measured from blood sample collection. A 5 to 50% change in serum creatine levels is expected;Perception of discomfort during preconditioning ischemia and perception of effort during eccentric exercise measured using the visual analogue scale (VAS) from 0 to 100 millimeters and the Borg scale, respectively. A change of 5 to 50% is expected in these outcomes

Countries

Brazil

Contacts

Public ContactMikhail Santos Cerqueira

Universidade Estadual do Sudoeste da Bahia

mikhail.cerqueira@uesb.edu.br+55 (73) 35289645

Outcome results

None listed

Source: REBEC (via WHO ICTRP)