Women with different genotypes of polymorphism of the Angiotensin Converting Enzyme (ACE)
Conditions
Interventions
Clinical randomized controlled trial, double-blind, 3 arms. Women between 18 and 49 years will be voluntarily recruited from the local community. Each volunteer you be submitted to general physical ex
2) Resistance training - will be performed with weekly and daily undulating periodization models. En the daily undulating model, training intensity will be increased in each day of the week, for examp
3) Anthropometry
4)Body composition - body composition analysis of the volunteers, before and after the training period will be done by the Dual-energy X-ray absorptiometry
5)Blood pressure - the measure of systolic (SBP) and diastolic blood pressure (DBP), in weeks 0, 12 and 24 will be done by the auscultatory method
6) Cytokines measure - plasma cytokines and resistin, and salivary immunoglobulin A - saliva drawn will be performed to remove cells from the oral mucosa. Then, swabs tips will be separated with sciss
other
E02.779.483.875
Sponsors
Universidade Católica de Brasília
Universidade Católica de Brasília
Eligibility
Sex/Gender
Female
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: To be pre-menopausal aged between 18-49 years and no regular practice of exercise in the previous 12 months
Exclusion criteria
Exclusion criteria: Use of drugs that could affect cardiovascular response to exercise and presence of any disease that would compromise their health during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of the metabolic profile measured by blood cytokines, lipidogram, insulin and glucose | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease of the cardiovascular risk factors, also measured by blood pressure parameters after six months | — |
Countries
Brazil
Contacts
Public ContactRamires Tibana
Universidade Católica de Brasília
Outcome results
None listed