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Effects of PEEP-ZEEP technique on pulmonary secretion removal and respiratory system.

Effects of PEEP-ZEEP Maneuver on pulmonary secretion clearance and respiratory mechanics

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6gdktv
Enrollment
Unknown
Registered
2018-01-15
Start date
2017-10-09
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-associated pneumonia. Prolonged mechanical ventilation. Mechanical ventilation weaning failure.

Interventions

Single group: 26 subjects will be positioned in dorsal decubitus and will be submitted to endotracheal suctioning. After 30 minutes, initial heart rate (HR), systolic blood pressure (SBP), diastolic b
Procedure/surgery
E02.779

Sponsors

Universidade Federal do Triângulo Mineiro
Lead Sponsor
Universidade Federal de São Paulo
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients with pulmonary secretion on mechanical invasive ventilation; hemodynamically stable (MBP higher than 65 mmHg); PEEP lower or equal than 10 cmH2O; oxygen inspiratory fraction lower or equal than 0,4; peripheral oxygen saturation higher than 90%.

Exclusion criteria

Exclusion criteria: Intracranial hypertension; cor pulmonale; pulmonary hypertension; pregnancy; pneumothorax not drained; bronchospasm; rib fractures.

Design outcomes

Primary

MeasureTime frame
Mean difference of suctioned pulmonary secretion of 1 g for the PEEP-ZEEP maneuver plus airway suctioning vs airway suctioning alone.

Secondary

MeasureTime frame
Equivalence on hemodynamics during the 30-minute-interval after PEEP-ZEEP plus airway suctioning vs airway suctioning alone.

Countries

Brazil

Contacts

Public ContactMarcia Volpe

Universidade Federal do Triângulo Mineiro

marciasvolpe@gmail.com+55(34)991832000

Outcome results

None listed

Source: REBEC (via WHO ICTRP)