obesity, insulin resistance
Conditions
Interventions
In this study, all volunteers recruited (9 obese insulin-sensitive and 9 obese insulin resistant) will receive the same intervention, it is aerobic exercise training program held in intervention will
Behavioural
G11.427.590.530.698.277
Sponsors
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Eligibility
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Body mass index equal to 30kg/m2 or superiror, non smokers and physically inactive. Volunteers should still provide stable body weight in the 3 months preceding the study, did not participate in programs to reduce weight in the last six months and not using drugs that can affect metabolism. For the group of resistant insulin, volunteers must submit insulin resistance evaluated from laboratory tests.
Exclusion criteria
Exclusion criteria: Reporting the presence of acute or chronic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean body mass index before and after 12 weeks of training.;Mean evaluation index of insulin resistance homeostasis (HOMA-IR); before and after 12 weeks of training.;Mean expression of proteins related to the stress / inflammation in skeletal muscle; before and after 12 weeks of training. | — |
Secondary
| Measure | Time frame |
|---|---|
| Composition of food intake (Proteins, carbohydrates and fats) assessed from 3-day food record, will be made every 15 days during the 12 weeks of training. | — |
Countries
Brazil
Contacts
Public ContactFabiano Amorim
Universidade Federal dos Vales do Jequitinhonha e Mucuri
Outcome results
None listed