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Evaluation of the effect of a neuromuscular blocker in patients undergoing gastric bypass surgery by videolaparoscopy

Evaluation of the effect of moderate and profound neuromuscular blockers in patients undergoing laparoscopic roux-en-y gastric bypass - The expanding acronym NBGAS is "Neuromuscular Block in Gastroplasty"

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6g2vcnx
Enrollment
Unknown
Registered
2024-05-21
Start date
2021-10-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

All patients will receive intravenous general anesthesia with propofol 2 mg.kg-1, fentanyl 3 mcg.kg-1, dexmedetomidine 0.5 mcg.kg-1 and rocuronium (dose depending on randomization). Intraoperatively,

Sponsors

Hospital São Domingos
Lead Sponsor
Hospital São Domingos
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: aged between 18 and 65 years, both sexes, with an ASA score from 1 to 3, undergoing roux-en-y gastric bypass by robotic surgery will be included in the study.

Exclusion criteria

Exclusion criteria: Patients with cardiac arrhythmias, dilated cardiomyopathy, cardiac conduction disorder, electrolyte disturbance, acid base disturbance, known or suspected allergies to drugs used during anesthesia, family history of neuromuscular disease, family history of malignant hyperthermia, and renal failure, psychiatric, hepatic, respiratory or oncological diseases, who are receiving any type of analgesic in the week before surgery and those who receive blood products during the study period.

Design outcomes

Primary

MeasureTime frame
Patients in the sustained deep neuromuscular blockade group are expected to obtain better surgical conditions with reduced postoperative pain and consequently lower postoperative pain scores. Assessment will be performed using questionnaires at defined times to check pain intensity, time of first request for opioid use and total opioid consumption in the first 24 hours.

Secondary

MeasureTime frame
No secondary results expected

Countries

Brazil

Contacts

Public ContactHiago Parreão Braga Braga

Hospital São Domingos

hiago_braga@hotmail.com+559832168100

Outcome results

None listed

Source: REBEC (via WHO ICTRP)