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Evaluation of the use of membranes obtained from blood centrifugation for gingival retraction repair surgeries in smoker patients

Evaluation of the use of Platelet Rich Fibrin for root coverage of Cairo Type I gingival recession in smoker patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6fxhwqw
Enrollment
Unknown
Registered
2025-02-11
Start date
2023-11-09
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival recession

Interventions

This is a split-mouth randomized clinical trial. Applied to 20 smoking patients (total of 40 teeth) aged between 20 and 55 years old, who had bilateral Cairo Type I gingival recessions. On one side of

Sponsors

UNIOESTE - Universidade Estadual do Oeste do Paraná
Lead Sponsor
Faculdade São Leopoldo Mandic
Collaborator

Eligibility

Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Smoking patients; with Cairo Type I gingival recession; bilateral; aged between 20 and 50 years; both genders; without comorbidities seeking treatment at the Unioeste Dentistry Clinic

Exclusion criteria

Exclusion criteria: Exclusion criteria include; individuals who do not meet the criteria of cigarette consumption > 10 cigarettes/day; positive history of antibiotic therapy in the last six months and anti-inflammatories; steroids or non-steroids; in the three months preceding the study; positive history of pregnancy; positive history of any systemic problem that contraindicates the surgical procedure; endodontic treatment or pulp pathology in the involved tooth; pathogenic occlusal interferences and previous surgery at the site

Design outcomes

Primary

MeasureTime frame
Primary - There is an improvement in the periodontal clinical parameters of areas with gingival recessions in both groups, since they are smokers with a lower healing response. For the parameters of height and width of gingival recessions, and width and thickness of keratinized tissue, it is expected that in cases of recession covered with PRF membrane, the same percentage gains will occur as in areas where connective tissue grafts were used (gold standard). ). Secondary - This is to establish an improvement in the periodontal clinical parameters of areas with gingival recession in all patients, as well as root coverage, formation of a good volume of keratinized tissue, improvement in sensitivity and aesthetic contour of the gingival margin.

Secondary

MeasureTime frame
This is to establish an improvement in the periodontal clinical parameters of areas with gingival recession in all patients, as well as root coverage, formation of a good volume of keratinized tissue, improvement in sensitivity and aesthetic contour of the gingival margin.

Countries

Brazil

Contacts

Public ContactAdriano Piccolotto

Universidade Estadual do Oeste do Paraná - UNIOESTE

adriano.piccolotto@unioeste.br+55 (45) 3220-3168

Outcome results

None listed

Source: REBEC (via WHO ICTRP)