Pain
Conditions
Interventions
This study will be a randomized, controlled, triple-blind clinical trial, using the split-mouth model, in which the first surgical intervention will be performed on one side of the arcade (right or le
Sponsors
Universidade Federal de Uberlândia
Universidade Federal de Uberlândia
Eligibility
Age
18 Years to 30 Years
Inclusion criteria
Inclusion criteria: Will be included in the study, 28 patients aged between 18 and 30 years and without impairment of general health according to medical history (healthy) and physical examination who agree to participate in the study. Through clinical and radiographic examination, asymptomatic patients with indication for bilateral extraction of mandibular third molars will be selected, in class IIB position, according to Pell & Gregory's classification.
Exclusion criteria
Exclusion criteria: Exclusion criteria will be considered: (I) history of use of any type of medication in the 15 days prior to the start of the surgical procedure; (II) history of hypersensitivity to drugs, substances or materials used in this experiment; (III) pregnancy or lactation; (IV) pericoronitis or other local infection within 15 days prior to the surgical procedure; (V) people with a history of systemic disease, such as hypertension, diabetes, or diseases with high oxidative stress, such as favism, severe anemia), (VI) and time of the shortest intervention less than 75% of the time elapsed in the longest intervention long.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presentation of the expected pain outcome, presentation of the method used to verify the expected visual analogue scale (VAS) outcome and presentation of the parameters number with two decimals used to verify if the outcome really was a difference between pre- and post-intervention pain with each blood concentrate.;Presentation of the expected outcome edema, presentation of the method used to verify the expected outcome linear measurements on the face and presentation of the parameters percentage difference between before and after used to verify if the outcome really occurred difference between pre and post-intervention edema with each blood concentrate.;Presentation of the expected outcome trismus, presentation of the method used to verify the expected outcome linear measurements of maximum mouth opening between the central incisors and presentation of the integer parameters used to verify if the outcome really was a difference between trismus pre and post-intervention with each blood concentrate. | — |
Secondary
| Measure | Time frame |
|---|---|
| Presentation of the expected outcome analgesic consumption, presentation of the method used to verify the expected outcome number of analgesic pills consumed and presentation of the parameters integer number of pills consumed used to verify if the outcome really was a difference between pre- and post-intervention analgesic consumption with each blood concentrate. | — |
Countries
Brazil
Contacts
Public ContactMarcelo Costa
Universidade Federal de Uberlândia
Outcome results
None listed