Mucositis
Conditions
Interventions
Dosimetry in intraoral stents.
20 patients with oral squamous cell carcinomas, who will undergo radiotherapy in the head and neck by linear accelerators Elekta Sinergy 6-MV. Patients will be selected
Other
E07.710.725
Sponsors
Instituto do Câncer do Estado de São Paulo
Faculdade de Odontologia de Piracicaba
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with oral squamous cell carcinomas (C02; C02.1; C04; C05; C10), who concluded a pre-radiotherapy oral compliance protocol with the ICESP Oncological Dentistry Service. Patients on an oral exclusive diet prior to radiotherapy and who will use oral stent during radiotherapy sessions. Patients should also be on the Institutional protocol Oncological Dentistry Service, with daily follow-up at the laser therapy clinic (photobiomodulation).
Exclusion criteria
Exclusion criteria: Will be excluded from our protocol patients with: - Squamous cell carcinomas in non-oral topographies; - Interruption of radiotherapy treatment; - Karnofsky scales below 40%; - Performing diet via nasogastric tube and gastrostomy before radiotherapy -Patients edentulous and not candidates for the use of oral stents according to the Institutional protocol; - Patients with non adherence to the laser therapy protocol, or up to 5 consecutive absences in outpatient laser therapy appoinment follow up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To characterize and validate the radiosensitivity and its correlation with development and progression of oral mucositis by means of in vivo dosimetry | — |
Secondary
| Measure | Time frame |
|---|---|
| To perform a comparative analysis between radiosensitivity to oral mucosal site associated with tumor topography of mouth tumors | — |
Countries
Brazil
Contacts
Public ContactKarina Morais Faria Barreto
Instituto do Câncer do Estado de São Paulo
Outcome results
None listed