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Comparison of the results of two different types of acids on the face of women with oily and blemished skin.

Comparison of effectiveness of chemical peeling of retinoic acid and mandellic acid on oleosity and acne hypercromy in adult women: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6d9657
Enrollment
Unknown
Registered
2017-07-28
Start date
2017-05-25
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris and postinflammatory hyperpigmentation

Interventions

Are involved in the study were 30 women randomly divided into 3 groups by a computer program. Being G1 group 10 women undergoing 03 biweekly sessions Pelling Retinoic Acid 5%, which will be applied to
G2 group 10 women undergoing 03 biweekly sessions Pelling Mandelic Acid 30%, which will be applied to the face and acting will be 5 to 10 minutes after will be removed with soap and water in abundance
Procedure/surgery
Other

Sponsors

Universidade Federal de Mato Grosso do Sul
Lead Sponsor
Universidade Federal de Mato Grosso do Sul
Collaborator

Eligibility

Sex/Gender
Female
Age
18 Years to 48 Years

Inclusion criteria

Inclusion criteria: Will be included female individuals, aged between 18 years and 48 years, with a phototype of I to IV and with complaint of hyperchromia after acne on the face verified by Baumman questionnaire

Exclusion criteria

Exclusion criteria: Pregnant and lactating women will be excluded who have is subjected to dermatological and / or cosmetic treatment in the face in the last 6 months, or who have active infection in the face (acne> grade I), disease dermatological or metabolic causing hyperpigmentation of the face, such as Syndrome Cushing's and Lupus Systemic Eritrematoso or hyperpigmentation from birth as nevus. Similarly, those who miss session 01 any of the groups are excluded

Design outcomes

Primary

MeasureTime frame
Expected a reduction of at least 30% in the degree of oiliness of the skin of women undergoing treatment with mandelic and mandelic acid in the control group. Reduction of at least 10% of the area hyperpigmentation, with uniformity of skin tone in women treated with mandelic acid and retinoic compared to the control group.;Reduction of at least 30% of the area of hyperpigmentation, with uniformity of skin tone in the women treated with mandelic acid and retinoic acid in comparison to the control group, evaluated by means of the comparison of the photographic records before the beginning and one week after the end of the intervention .

Secondary

MeasureTime frame
Promoting improvement of at least 30% the aesthetic aspect of the skin in all the women involved in the present study evaluated through the global self-satisfaction scale before and one week after the end of the intervention.

Countries

Brazil

Contacts

Public ContactAna Beatriz Pegorare

Universidade Federal de Mato Grosso do Sul

anabegs@gmail.com+55 (67)33457836

Outcome results

None listed

Source: REBEC (via WHO ICTRP)